LanthaScreen® TR-FRET ROR gamma Coactivator Assay Kit, goat - Citations

LanthaScreen® TR-FRET ROR gamma Coactivator Assay Kit, goat - Citations

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Citations & References
Abstract
Ursolic acid suppresses interleukin-17 (IL-17) production by selectively antagonizing the function of RORgamma t protein.
AuthorsXu T, Wang X, Zhong B, Nurieva RI, Ding S, Dong C,
JournalJ Biol Chem
PubMed ID21566134
Th17 cells have recently emerged as a major player in inflammatory and autoimmune diseases via the production of pro-inflammatory cytokines IL-17, IL-17F, and IL-22. The differentiation of Th17 cells and the associated cytokine production is directly controlled by ROR?t. Here we show that ursolic acid (UA), a small molecule present ... More