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Invitrogen
AKT1 Polyclonal Antibody
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产品信息
PY-10178
产品规格
宿主/亚型
Chicken
分类
Polyclonal
类型
Antibody
抗原
KT fusion protein.
偶联物
Unconjugated
Unconjugated
Unconjugated
形式
Lyophilized
规格
100 µg
保存条件
-20°C, Avoid Freeze/Thaw Cycles
运输条件
Wet ice
产品详细信息
PY-10178 detects AKT1 in human, mouse and rat samples.
PY-10178 has been successfully used in ELISA procedures.
The PY-10178 immunogen is a KT fusion proteincorresponding to residues 106-122.
Reconstitute using 100 ul of distilled water to restore the original concentration to 1 mg/ml.
靶标信息
AKT1 (PKB alpha) is a serine/threonine kinase that regulates cell survival. The activated enzyme inhibits apoptosis and stimulates cell cycle progression by phosphorylating numerous targets in various cell types, including cancer cells. This protein kinase is activated by insulin, PI3K, IGF1 and various other growth and survival factors. Akt promotes cell survival by inhibiting apoptosis through phosphorylation and inactivation of several targets, including forkhead transcription factors, and caspase-9. The AKT pathway is a major target for cancer drug discovery.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
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