Synthesis and characterization of polymer-coated quantum dots with integrated acceptor dyes as FRET-based nanoprobes.
AuthorsFernandez-Argüelles MT, Yakovlev A, Sperling RA, Luccardini C, Gaillard S, Medel AS, Mallet JM, Brochon JC, Feltz A, Oheim M, Parak WJ,
JournalNano Lett
PubMed ID17691850
A fluorescence resonance energy transfer pair consisting of a colloidal quantum dot donor and multiple organic fluorophores as acceptors is reported and the photophysics of the system is characterized. Most nanoparticle-based biosensors reported so far use the detection of specific changes of the donor/acceptor distance under the influence of analyte ... More
The impact of different nanoparticle surface chemistry and size on uptake and toxicity in a murine macrophage cell line.
AuthorsClift MJ, Rothen-Rutishauser B, Brown DM, Duffin R, Donaldson K, Proudfoot L, Guy K, Stone V,
JournalToxicol Appl Pharmacol
PubMed ID18708083
This study investigated the uptake, kinetics and cellular distribution of different surface coated quantum dots (QDs) before relating this to their toxicity. J774.A1 cells were treated with organic, COOH and NH2 (PEG) surface coated QDs (40 nM). Model 20 nm and 200 nm COOH-modified coated polystyrene beads (PBs) were also ... More