The acute environment, rather than T cell subset pre-commitment, regulates expression of the human T cell cytokine amphiregulin.
AuthorsQi Y, Operario DJ, Georas SN, Mosmann TR
JournalPLoS One
PubMed ID22720031
'Cytokine expression patterns of T cells can be regulated by pre-commitment to stable effector phenotypes, further modification of moderately stable phenotypes, and quantitative changes in cytokine production in response to acute signals. We showed previously that the epidermal growth factor family member Amphiregulin is expressed by T cell receptor-activated mouse ... More