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Invitrogen
Human Growth Hormone Recombinant Protein
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Product Details
RP-10912
Product Specifications
Species
Human
Expression System
E. coli
Amino acid sequence
Human Growth Hormone recombinant protein contains 192 amino acids
Molecular weight
22.260 kDa
Class
Recombinant
Type
Protein
Endotoxin concentration
<0.1 ng/µg
Activity
Fully biologically active as compared to WHO reference standard at 3 U/mg.
Conjugate
Unconjugated
Unconjugated
Unconjugated
Form
Lyophilized
Concentration
100 µg/mL
Amount
500 µg
Purification
purified
Storage buffer
PBS with 1mg mannitol, 1mg glycine
Contains
no preservative
Storage conditions
-20°C, Avoid Freeze/Thaw Cycles
Shipping conditions
Wet ice
Product Specific Information
This is a recombinant protein suitable for use as a control in ELISA and Western blot applications.
Store lyophilized product desiccated at -20° C. Upon reconstitution, store at 4° C for 2-7 days or aliquot and store at -20° C. For long term storage add either HSA or BSA to 0.1%. Avoid repeated freeze/thaw cycles.
Reconstitute using distilled water to a concentration not less than 100 µg/mL.
Target Information
Human growth hormone (hGH) is a member of the somatotropin/prolactin family of hormones which play an important role in growth control. The GH1 gene, along with 4 additional related genes, is located at the growth hormone locus on chromosome 17. The five genes share a remarkably high degree of sequence identity. Alternative splicing results in 5 isoforms ranging from approximately 19 kDa to 24 kDa. HGH is produced by the somatotroph cells in the pituitary. It acts through binding to membrane receptors that belong to the cytokine receptor subfamily. Its major role in stimulating body growth is to stimulate the liver and other tissues to secrete IGF-1. It stimulates both the differentiation and proliferation of myoblasts. It also stimulates amino acid uptake and protein synthesis in muscle and other tissues. Mutations or deletions in the gene lead to growth hormone deficiency and short stature.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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Bioinformatics
Protein Aliases: GH; GH1; Growth hormone; Growth hormone 1; growth hormone B5; HGH; Pituitary growth hormone; rHGH; Somatotropin; unnamed protein product
Gene Aliases: GH; GH-N; GH1; GHB5; GHN; hGH-N; IGHD1A; IGHD1B; IGHD2
UniProt ID: (Human) P01241
Entrez Gene ID: (Human) 2688
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