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Invitrogen
Human p53 mutant (aa135) Recombinant Protein
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产品信息
RP-39231
产品规格
Expression System
E. coli
分类
Recombinant
类型
Protein
偶联物
Unconjugated
Unconjugated
Unconjugated
形式
Liquid
浓度
0.1 mg/mL
Amount
10 µg
保存条件
-20°C or -80°C if preferred
运输条件
Wet ice
产品详细信息
This product is a GST-tagged recombinant protein corresponding to full-length human p53 mutant, aa135.
On SDS-PAGE commassie blue stained gel, the purified recombinant protein shows a band at 81kDa.
靶标信息
This gene encodes a tumor suppressor protein containing transcriptional activation, DNA binding, and oligomerization domains. The encoded protein responds to diverse cellular stresses to regulate expression of target genes, thereby inducing cell cycle arrest, apoptosis, senescence, DNA repair, or changes in metabolism. Mutations in this gene are associated with a variety of human cancers, including hereditary cancers such as Li-Fraumeni syndrome. Alternative splicing of this gene and the use of alternate promoters result in multiple transcript variants and isoforms. Additional isoforms have also been shown to result from the use of alternate translation initiation codons.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
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