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Invitrogen
HIV1 nef Recombinant Protein
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产品信息
RP-4922
产品规格
Expression System
E. coli
分类
Recombinant
类型
Protein
偶联物
Unconjugated
Unconjugated
Unconjugated
形式
Liquid
浓度
0.48 mg/mL
Amount
20 µg
保存条件
-20°C, Avoid Freeze/Thaw Cycles
运输条件
Wet ice
产品详细信息
RP-4922 can be used as a positive control in Western blotting with ABR antibody anti-HIV-1 Nef (PA1-4961, PA1-4962, or PA1-4963), as well as a HIV-1Nef antigen in detection of anti-HIV-1 Nef antibody in Western blotting or ELISA.
RP-4922 has a calculated molecular weight of ~27 kDa.
Purity is 90%.
靶标信息
HIV-1 Nef is one of the accessory proteins synthesized in the early stage of AIDS virus reproduction and is abundantly found in infected cells. The name derives from its negative factor thought at the beginning but presently it is remarked as the protein which bears a most distinctive biological characteristic of AIDS virus. The protein interacts directly with the signal transduction protein of the host T cell and works effectively on AIDS infection or on long term survival of the infected cells or induces apoptosis of non-infected cells. It is also involved in the endocytosis and degradation of receptor protein of the cell surface such as CD 4 and MH4, important for AIDS virus infection.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
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