Sex-specific differences in mouse DMRT1 expression are both cell type- and stage-dependent during gonad development.
AuthorsLei N, Hornbaker KI, Rice DA, Karpova T, Agbor VA, Heckert LL,
JournalBiol Reprod
PubMed ID17567962
Immunohistochemistry was used to examine GCNA1, a germ cell-specific protein, together with DMRT1 (Doublesex and Mab-3-related transcription factor-1), a transcription factor implicated in Sertoli cell and germ cell function, in order to resolve DMRT1's cellular profile during pre- and postnatal gonad development in the mouse. In the indifferent gonad (10.5-11.5 ... More