Exercise reduces GABA synaptic input onto nucleus tractus solitarii baroreceptor second-order neurons via NK1 receptor internalization in spontaneously hypertensive rats.
AuthorsChen CY, Bechtold AG, Tabor J, Bonham AC,
JournalJ Neurosci
PubMed ID19261870
'A single bout of mild to moderate exercise can lead to a postexercise decrease in blood pressure in hypertensive subjects, namely postexercise hypotension (PEH). The full expression of PEH requires a functioning baroreflex, hypertension, and activation of muscle afferents (exercise), suggesting that interactions in the neural networks regulating exercise and ... More
Detection of allergen-specific IgE on microarrays by use of signal amplification techniques.
AuthorsBacarese-Hamilton T, Mezzasoma L, Ingham C, Ardizzoni A, Rossi R, Bistoni F, Crisanti A
JournalClin Chem
PubMed ID12142398
The actin-based motor protein myosin II regulates MHC class II trafficking and BCR-driven antigen presentation.
AuthorsVascotto F, Lankar D, Faure-André G, Vargas P, Diaz J, Le Roux D, Yuseff MI, Sibarita JB, Boes M, Raposo G, Mougneau E, Glaichenhaus N, Bonnerot C, Manoury B, Lennon-Duménil AM
JournalJ Cell Biol
PubMed ID17389233
Antigen (Ag) capture and presentation onto major histocompatibility complex (MHC) class II molecules by B lymphocytes is mediated by their surface Ag receptor (B cell receptor [BCR]). Therefore, the transport of vesicles that carry MHC class II and BCR-Ag complexes must be coordinated for them to converge for processing. In ... More
Identifying antimicrobial resistance genes with DNA microarrays.
AuthorsCall DR, Bakko MK, Krug MJ, Roberts MC
JournalAntimicrob Agents Chemother
PubMed ID14506043
We developed and tested a glass-based microarray suitable for detecting multiple tetracycline (tet) resistance genes. Microarray probes for 17 tet genes, the beta-lactamase bla(TEM-1) gene, and a 16S ribosomal DNA gene (Escherichia coli) were generated from known controls by PCR. The resulting products (ca. 550 bp) were applied as spots ... More