Tubulin Tracker™ Green (Oregon Green™ 488 Taxol, bis-acetate)
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Tubulin Tracker™ Green (Oregon Green™ 488 Taxol, bis-acetate)
Invitrogen™

Tubulin Tracker™ Green (Oregon Green™ 488 Taxol, bis-acetate)

Tubulin Tracker Green (Oregon Green 488 Taxol, bis-acetate) provides green-fluorescent staining of polymerized tubulin in live cells. Tubulin Tracker GreenRead more
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Catalog NumberQuantity
T3407860 slides
Catalog number T34078
Price (CNY)
1,382.00
Online Exclusive
Ends: 31-Dec-2025
1,873.00
Save 491.00 (26%)
60 slides
Add to cart
Quantity:
60 slides
Price (CNY)
1,382.00
Online Exclusive
Ends: 31-Dec-2025
1,873.00
Save 491.00 (26%)
60 slides
Add to cart
Tubulin Tracker Green (Oregon Green 488 Taxol, bis-acetate) provides green-fluorescent staining of polymerized tubulin in live cells. Tubulin Tracker Green is an uncharged, non-fluorescent compound that easily passes through the plasma membrane of live cells. Once inside the cell, the lipophilic blocking group is cleaved by non-specific esterases, resulting in a green-fluorescent, charged form, inhibiting it from escaping the live cells. TubulinTracker Green reagent utilizes Oregon Green 488 dye, which absorbs and emits optimally at 494 nm and 522 nm, respectively, and fluorescence can be visualized with standard GFP/FITC filter settings using almost any fluorescent imaging instrument. It can be multiplex with blue, orange, red, deep-red, and near-IR fluorophores.

Visualize staining your cell without wasting your reagents, antibodies, or time with our new Stain-iT Cell Staining Simulator.

For Research Use Only. Not for use in diagnostic procedures.
Specifications
Dye TypeOregon Green™ 488
Excitation Wavelength Range494/522
Product LineTubulinTracker
Quantity60 slides
Shipping ConditionApproved for shipment on Wet or Dry Ice
Label TypeUV-Vis Labels
Product TypeTubulin Tracker
SubCellular LocalizationTubulin
Unit Size60 slides
Contents & Storage
Contains sufficient material for at least 60 slides at 1 mL / slide and 1 x working concentration.

1 x 20 μg Tubulin Tracker Green (Oregon Green 488 Taxol, bis-acetate)

1 x 1 mL Pluronic F-127, 20% solution in DMSO

Frequently asked questions (FAQs)

What is the difference between Tubulin Tracker Green (Cat No. T34078) and Tubulin Tracker Green, for live cell imaging (Cat. No. T34075)?

Both products include the same Tubulin Tracker Green reagent. The difference is in the packaging and amount of Tubulin Tracker Green reagent contained. Tubulin Tracker Green, for live cell imaging (Cat. No. T34075) includes enough Tubulin Tracker Green reagent for 300 slides whereas Tubulin Tracker Green (Cat No. T34078) contains enough Tubulin Tracker Green reagent for 60 slides. Also, Tubulin Tracker Green, for live cell imaging (Cat. No. T34075) does not include Probenecid.

Find additional tips, troubleshooting help, and resources within our Cell Analysis Support Center.

With Tubulin Tracker Deep Red and Tubulin Tracker Green, can I fix samples after labeling?

No. The labeling is not retained upon fixation. Imaging of the samples should be done only on live cells. To limit photobleaching while viewing live cells, use ProLong Live Antifade Reagent, for live cell imaging (Cat No. P36974 and P36975).

Find additional tips, troubleshooting help, and resources within our Cell Analysis Support Center.

How is Docetaxel in Tubulin Tracker Deep Red different from Taxol in Tubulin Tracker Green? Are there any differences in the binding or cytotoxicity between the two reagents?

Docetaxel has a slightly higher binding affinity than Taxol and exhibits longer retention time due to better uptake and slower efflux, but for use in labeling cultured cells, these differences should be minimal. More information comparing the properties of these two reagents is provided in this publication: https://www.ncbi.nlm.nih.gov/pubmed/1671606 https://www.cell.com/fulltext/S1074-5521(05)00301-7

Find additional tips, troubleshooting help, and resources within our Cell Analysis Support Center.

Citations & References (9)

Citations & References
Abstract
Involvement of 14-3-3 in tubulin instability and impaired axon development is mediated by Tau.
Authors:Joo Y, Schumacher B, Landrieu I, Bartel M, Smet-Nocca C, Jang A, Choi HS, Jeon NL, Chang KA, Kim HS, Ottmann C, Suh YH,
Journal:
PubMed ID:26103986
'14-3-3 proteins act as adapters that exert their function by interacting with their various protein partners. 14-3-3 proteins have been implicated in a variety of human diseases including neurodegenerative diseases. 14-3-3 proteins have recently been reported to be abundant in the neurofibrillary tangles (NFTs) observed inside the neurons of brains ... More
Impact of C24:0 on actin-microtubule interaction in human neuronal SK-N-BE cells: evaluation by FRET confocal spectral imaging microscopy after dual staining with rhodamine-phalloidin and tubulin tracker green.
Authors:Zarrouk A, Nury T, Dauphin A, Frère P, Riedinger JM, Bachelet CM, Frouin F, Moreau T, Hammami M, Kahn E, Lizard G,
Journal:
PubMed ID:26214025
'Disorganization of the cytoskeleton of neurons has major consequences on the transport of neurotransmitters via the microtubule network. The interaction of cytoskeleton proteins (actin and tubulin) was studied in neuronal SK-N-BE cells treated with tetracosanoic acid (C24:0), which is cytotoxic and increased in Alzheimer''s disease patients. When SK-N-BE cells were ... More
The Ovary of Tubifex tubifex (Clitellata, Naididae, Tubificinae) Is Composed of One, Huge Germ-Line Cyst that Is Enriched with Cytoskeletal Components.
Authors:Urbisz AZ, Chajec L, Swiatek P,
Journal:
PubMed ID:26001069
Recent studies on the ovary organization and oogenesis in Tubificinae have revealed that their ovaries are small polarized structures that are composed of germ cells in subsequent stages of oogenesis that are associated with somatic cells. In syncytial cysts, as a rule, each germ cell is connected to the central ... More
Multimodal two-photon imaging using a second harmonic generation-specific dye.
Authors:Nuriya M, Fukushima S, Momotake A, Shinotsuka T, Yasui M, Arai T,
Journal:Nat Commun
PubMed ID:27156702
'Second harmonic generation (SHG) imaging can be used to visualize unique biological phenomena, but currently available dyes limit its application owing to the strong fluorescent signals that they generate together with SHG. Here we report the first non-fluorescent and membrane potential-sensitive SHG-active organic dye Ap3. Ap3 is photostable and generates ... More
Tubulin is a molecular target of the Wnt-activating chemical probe.
Authors:Fukuda Y, Sano O, Kazetani K, Yamamoto K, Iwata H, Matsui J,
Journal:BMC Biochem
PubMed ID:27207629
In drug discovery research, cell-based phenotypic screening is an essential method for obtaining potential drug candidates. Revealing the mechanism of action is a key step on the path to drug discovery. However, elucidating the target molecules of hit compounds from phenotypic screening campaigns remains a difficult and troublesome process. Simple ... More