Exocytosis of IgG as mediated by the receptor, FcRn: an analysis at the single-molecule level.
Authors:Ober RJ, Martinez C, Lai X, Zhou J, Ward ES
Journal:Proc Natl Acad Sci U S A
PubMed ID:15258288
'IgG transport within and across cells is essential for effective humoral immunity. Through a combination of biochemical and in vivo analyses, the MHC class I-related neonatal Fc receptor (FcRn) is known to play a central role in delivering IgGs within and across cells. However, little is known about the molecular ... More