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引用和文献 (27)
Invitrogen™
FM™ 2-10（N-(3-三乙基铵丙基)-4-(4-(二乙氨基)苯乙烯基)吡啶二溴盐）
FM™ 2-10 膜探针是一种出色的试剂，可用于鉴定主动应激神经元，研究活性依赖性囊泡循环机制。这种水溶性染料对细胞无毒且在水溶介质中几乎不发荧光，在插入细胞膜外层中后发出明亮的荧光。在主动释放神经递质的神经元中，染料会在可回收突触囊泡中内化，导致神经末端明亮染色。了解更多信息
| 货号 | 数量 |
|---|---|
| T7508 | 5 mg |
货号 T7508
价格（CNY)
4,145.00
飞享价
Ends: 31-Dec-2025
5,619.00共减 1,474.00 (26%)
5 mg
数量:
5 mg
价格（CNY)
4,145.00
飞享价
Ends: 31-Dec-2025
5,619.00共减 1,474.00 (26%)
5 mg
FM™ 2-10 膜探针是一种出色的试剂，可用于鉴定主动应激神经元，研究活性依赖性囊泡循环机制。这种水溶性染料对细胞无毒且在水溶介质中几乎不发荧光，在插入细胞膜外层中后发出明亮的荧光。在主动释放神经递质的神经元中，染料会在可回收突触囊泡中内化，导致神经末端明亮染色。
仅供科研使用。不可用于诊断程序。
规格
颜色橙色
检测方法荧光
适用于（设备）荧光显微镜
产品线FM
数量5 mg
运输条件室温
标签类型Fluorescent Dye
产品类型探头
亚细胞定位细胞膜
Unit Size5 mg
内容与储存
室温避光储存。
常见问题解答 (FAQ)
I want to study endosome trafficking using FM 4-64 dye. Will the label be retained after fixation? And can I label cells that have already been fixed?
引用和文献 (27)
引用和文献
Abstract
Ba2+ does not support synaptic vesicle retrieval in rat cerebrocortical synaptosomes.
Journal:Neurosci Lett
PubMed ID:9754790
To investigate whether any specific requirement for extracellular Ca2+ exists in the control synaptic vesicle retrieval, we examined the ability of the divalent cation Ba2+ to substitute for Ca2+ in both vesicle exocytosis and endocytosis. Ba2+ stimulated glutamate release from rat cerebrocortical synaptosomes. Ba2+-evoked release was inhibited by bafilomycin A1,
Frequency dependence of synaptic vesicle exocytosis in aortic baroreceptor neurons and the role of group III mGluRs.
Journal:Brain Res
PubMed ID:15051525
Synaptic transmission between baroreceptor afferents and the nucleus tractus solitarius (NTS) is essential for reflex regulation of blood pressure. High frequency stimulation of the afferents in vivo leads to a decrease in synaptic strength and is generally attributed to reduction in presynaptic neurotransmitter release. It has been hypothesized that during
Long-term staining of live Merkel cells with FM dyes.
Journal:Cell Tissue Res
PubMed ID:12658440
'Live Merkel cells in the skin and hair follicles are known to incorporate a fluorescence dye, quinacrine, which has been utilized to identify and dissect the cells for experiments. Quinacrine fluorescence of the cells is, however, quickly lost and quinacrine-stained Merkel cells soon become difficult to identify in tissue culture.
Two mechanisms of synaptic vesicle recycling in rat brain nerve terminals.
Journal:J Neurochem
PubMed ID:10987846
'KCl and 4-aminopyridine (4-AP) evoke glutamate release from rat brain cortical nerve terminals by voltage clamping or by Na(+) channel-generated repetitive action potentials, respectively. Stimulation by 4-AP but not KCl is largely mediated by protein kinase C (PKC). To determine whether KCl and 4-AP utilise the same mechanism to release
Calcium triggers calcineurin-dependent synaptic vesicle recycling in mammalian nerve terminals.
Journal:Curr Biol
PubMed ID:9651678
'BACKGROUND: Following exocytosis at the synapse, synaptic vesicle components are recovered by endocytosis. Morphological analysis has suggested that this occurs by a clathrin-mediated pathway, and the GTPase dynamin is thought to be involved in ''pinching off'' endocytosing vesicles. The finding that the calcium-dependent phosphatase calcineurin can dephosphorylate dynamin and two