Evidence that distinct states of the integrin alpha6beta1 interact with laminin and an ADAM.
AuthorsChen MS, Almeida EA, Huovila AP, Takahashi Y, Shaw LM, Mercurio AM, White JM
JournalJ Cell Biol
PubMed ID9971748
Integrins can exist in different functional states with low or high binding capacity for particular ligands. We previously provided evidence that the integrin alpha6beta1, on mouse eggs and on alpha6-transfected cells, interacted with the disintegrin domain of the sperm surface protein ADAM 2 (fertilin beta). In the present study we ... More