Wiskott-Aldrich syndrome protein is a key regulator of the phagocytic cup formation in macrophages.
AuthorsTsuboi S, Meerloo J,
JournalJ Biol Chem
PubMed ID17890224
'Phagocytosis is a vital first-line host defense mechanism against infection involving the ingestion and digestion of foreign materials such as bacteria by specialized cells, phagocytes. For phagocytes to ingest the foreign materials, they form an actin-based membrane structure called phagocytic cup at the plasma membranes. Formation of the phagocytic cup ... More