Functional studies of yeast-expressed human heart muscle carnitine palmitoyltransferase I.
AuthorsZhu H, Shi J, de Vries Y, Arvidson DN, Cregg JM, Woldegiorgis G
JournalArch Biochem Biophys
PubMed ID9344464
'Long-chain fatty acids are the primary source of energy production in the heart. Carnitine palmitoyltransferase I (CPT-I) catalyzes the first reaction in the transport of long-chain fatty acids from the cytoplasm to the mitochondrion, a rate-limiting step in beta-oxidation. In this study, we report the functional expression of the human ... More