Intercellular trafficking and protein delivery by a herpesvirus structural protein.
AuthorsElliott G, O'Hare P,
JournalCell
PubMed ID9008163
We show that the HSV-1 structural protein VP22 has the remarkable property of intercellular transport, which is so efficient that following expression in a subpopulation the protein spreads to every cell in a monolayer, where it concentrates in the nucleus and binds chromatin. VP22 movement was observed both after delivery ... More