Search
Thermo Scientific™
PDPH（3-(2-吡啶基二硫基)丙酰肼）
Thermo Scientific Pierce PDPH is a short, pyridyldithiol-and-hydrazide crosslinker for reversibly conjugating sulfhydryls (cysteines) to carbonyls (aldehyde or ketones, such了解更多信息
| 货号 | 数量 |
|---|---|
| 22301 | 50 mg |
货号 22301
价格（CNY)
3,231.00
飞享价
Ends: 31-Dec-2025
4,124.00共减 893.00 (22%)
Each
数量:
50 mg
价格（CNY)
3,231.00
飞享价
Ends: 31-Dec-2025
4,124.00共减 893.00 (22%)
Each
Thermo Scientific Pierce PDPH is a short, pyridyldithiol-and-hydrazide crosslinker for reversibly conjugating sulfhydryls (cysteines) to carbonyls (aldehyde or ketones, such as those formed by oxidation of glycoprotein carbohydrates).
Features of PDPH :
• Reactive groups: pyridyldisulfide and hydrazide
• Reactive toward: sulfhydryl groups and carbonyl (aldehyde) groups
• Short (9.2A), sulfhydryl-to-aldehyde crosslinker with disulfide bond spacer arm (cleavable)
• Pyridyldithiol group results in attachment to sulfhydryls via disulfide bond, which can be cleaved with DTT, TCEP or other reducing agents
• Hydrazide group conjugates to oxidized sugars of glycoproteins and carbohydrates
• Use sodium meta-periodate to oxidize glycosylation (e.g., sialic acid) to reactive aldehyde groups
• Use with EDC to conjugate primary amine of hydrazide group to carboxyl groups
Product References:
Crosslinker Application Guide -- search for recent literature references for this product
Features of PDPH :
• Reactive groups: pyridyldisulfide and hydrazide
• Reactive toward: sulfhydryl groups and carbonyl (aldehyde) groups
• Short (9.2A), sulfhydryl-to-aldehyde crosslinker with disulfide bond spacer arm (cleavable)
• Pyridyldithiol group results in attachment to sulfhydryls via disulfide bond, which can be cleaved with DTT, TCEP or other reducing agents
• Hydrazide group conjugates to oxidized sugars of glycoproteins and carbohydrates
• Use sodium meta-periodate to oxidize glycosylation (e.g., sialic acid) to reactive aldehyde groups
• Use with EDC to conjugate primary amine of hydrazide group to carboxyl groups
Product References:
Crosslinker Application Guide -- search for recent literature references for this product
仅供科研使用。不可用于诊断程序。
规格
细胞渗透性是
描述PDPH
形式粉末
标记方法化学标记
分子量229.32
聚乙二醇化否
产品线Pierce™
数量50 mg
反应一部分酰肼、吡啶二硫化物
运输条件环境
溶解度DMF、DMSO
间隔臂长9.2 Å
水溶性否
化学反应性碳水化合物-巯基
可裂解用硫醇
交联剂类型异型双功能团试剂
产品规格标准
产品类型交联剂
间隔子短 (<10 Å)
Unit SizeEach
内容与储存
接收后，请在 4°C 下干燥储存。