TheraPure™ iBu-rG 亚磷酰胺,广口瓶
Thermo Scientific™

TheraPure™ iBu-rG 亚磷酰胺,广口瓶

iBu-rG CEP is a phosphoramidite containing 5' DMT and the nucleoside guanosine (G) with isobutyryl (iBu) base protection, for use in oligonucleotide synthesis.
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货号数量
27-1906-5050 g
货号 27-1906-50
价格(CNY)
6,969.00
Each
数量:
50 g
价格(CNY)
6,969.00
Each

iBu-rG CEP is a phosphoramidite containing 5' DMT and the nucleoside guanosine (G) with isobutyryl (iBu) base protection, for use in oligonucleotide synthesis. RNA phosphoramidites contain a 2'-OH protecting group, tBDMS (tert-butyl dimethylsilyl). Each base has unique protecting groups designed specifically to protect the RNA during the chemical synthesis process, and produce the highest amount of full length product. Alternate base protection options are also available to allow for faster deprotection and longer oligonucleotide synthesis. The TheraPure trademark denotes our highest level of phosphoramidite purity, developed with the greatest stringency of high definition analytics and tightly controlled impurity profiles and, therefore, ideal for any therapeutic application. This product is supplied in a 250 mL Opaque bottle with a Wide Mouth neck style, which is compatible with most None (Bulk) of oligonucleotide synthesizers.

Features:

  • HPLC Purity: ≥99%
  • M-11 Impurity: ≤0.01%
  • 31P NMR Purity: ≥99%
  • Sum of non-primary peaks in 140-152 ppm range: ≤0.5%
  • No single PIII impurity >0.3%
iBu-rG CEP 是一种亚磷酰胺,含 5' DMT 和具有异丁酰 (iBu) 碱基保护的鸟苷 (G),用于合成寡核苷酸。RNA 亚磷酰胺含有 2'-OH 保护基团、tBDMS(叔丁基二甲基硅烷基)。每种碱基均具有独特的保护基团,专用于在化学合成过程中保护 RNA,以及产生较高量的全长产物。也提供其他碱基保护,以实现脱保护,延长寡核苷酸合成。带有 TheraPure 商标的产品亚磷酰胺纯度均较高,因为在开发这种产品时,采用的是严格度较高的高分辨率分析方法,并且对杂质谱也进行了严格控制,因此,适用于任何治疗性应用。该产品以 250 mL 不透明瓶装,采用广口瓶颈样式,与大多数 None (Bulk) 寡核苷酸合成仪兼容。

特点:
•化学全称—5'-O-(4,4'-二甲氧基三苯甲基)-N2-异丁酰基-2'-O-[(叔丁基)二甲基硅烷基]-鸟苷-3'-O-[(2-氰乙基)-(N,N-二异丙基)]-亚磷酰胺
• 分子式—C50H68N7O9PSi
• 碱基—rG
• 碱基保护—iBu
• 化学式量—970.1 g/mol
• CAS 号—147201-04-5
• HPLC 纯度—≥99%;M-11 杂质:≤0.01%
• 31P NMR 纯度—≥99%;140-152 ppm 的非主峰总和:≤0.5%;无单个 PIII 杂质 >0.3%

仅供科研使用。不可用于诊断程序。
规格
31P NMR 纯度≥99%
CAS147201-04-5
化学名称或材料5'-O-(4,4'-Dimethoxytrityl)-N2-isobutyryl-2'-O-[(tert-butyl)dimethylsilyl]-guanosine-3'-O-[(2-cyanoethyl)-(N,N-diisopropyl)]-phosphoramidite
描述Base: rG
Base Protection: iBu
适用于(应用)Oligonucleotide synthesis
形式Powder
产品规格粉末
分级TheraPure™
分子式C50H68N7O9Psi
分子量970.1 g/mol
核酸类型RNA
核苷类型鸟苷 (G)
产品类型iBu-rG CEP
纯度≥99%
数量50 g
试剂类型亚磷酰胺
运输条件室温
产品线TheraPure
Unit SizeEach
内容与储存
在冰箱(-20°C 或以下)中储存。