PMPI（p-马来酰亚胺基苯基异氰酸盐）
PMPI（p-马来酰亚胺基苯基异氰酸盐）
引用和文献 (4)
Thermo Scientific™

PMPI（p-马来酰亚胺基苯基异氰酸盐）

Thermo Scientific Pierce PMPI 是一种马来酰亚胺和异氰酸盐交联剂，通过尿烷（氨基甲酸酯）键将连接子偶联到分子上的羟基，然后将化合物连接至巯基（半胱氨酸）。PMPI了解更多信息
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货号数量
2810050 mg
货号 28100
价格（CNY)
4,441.00
Each
添加至购物车
数量:
50 mg
请求批量或定制报价
价格（CNY)
4,441.00
Each
添加至购物车
Thermo Scientific Pierce PMPI 是一种马来酰亚胺和异氰酸盐交联剂，通过尿烷（氨基甲酸酯）键将连接子偶联到分子上的羟基，然后将化合物连接至巯基（半胱氨酸）。

PMPI 的特点：

•反应性基团：马来酰亚胺和异氰酸盐
• 可与以下基团发生反应：巯基和羟基
• 含芳香族间隔臂的短 (8.7A) 巯基-羟基交联剂（不可切割）
•马来酰亚胺基团与巯基反应形成稳定的硫醚键
• 异氰酸盐与非水性羟基反应形成氨基甲酸酯连接
• 用于偶联含羟基化合物（如类固醇和维生素）的出色工具
• 靶标和反应溶液不得含伯胺
仅供科研使用。不可用于诊断程序。
规格
细胞渗透性Not determined
描述PMPI
形式实心
标记方法化学标记
分子量307.1
聚乙二醇化否
产品线Pierce
数量50 mg
反应一部分马来酰亚胺、异氰酸盐
运输条件环境
溶解度DMF、DMSO
间隔臂长8.7 Å
水溶性否
化学反应性碳水化合物-巯基，羧基-巯基
可裂解否
交联剂类型异型双功能团试剂
产品规格标准
产品类型交联剂
间隔子短 (<10 Å)
Unit SizeEach
内容与储存
接收后，在 4°C 下防潮储存。

引用和文献 (4)

引用和文献
Abstract
X-ray photoelectron spectroscopy and infrared spectroscopy study of maleimide-activated supports for immobilization of oligodeoxyribonucleotides.
Authors:Shen G, Anand MF, Levicky R
Journal:Nucleic Acids Res
PubMed ID:15537837
'Surface-tethered nucleic acids are widely applied in solid-phase assays in which complementary strands must be detected against a complex mixture of other sequences. In response to such needs, numerous methods have been developed for immobilizing nucleic acids on solid supports. Often, detailed analysis of associated chemical transformations and of potential ... More
Direct electrical detection of DNA synthesis.
Authors:Pourmand N, Karhanek M, Persson HH, Webb CD, Lee TH, Zahradníková A, Davis RW
Journal:Proc Natl Acad Sci U S A
PubMed ID:16614066
'Rapid, sequence-specific DNA detection is essential for applications in medical diagnostics and genetic screening. Electrical biosensors that use immobilized nucleic acids are especially promising in these applications because of their potential for miniaturization and automation. Current DNA detection methods based on sequencing by synthesis rely on optical readouts; however, a ... More
Discovering ligands for a microRNA precursor with peptoid microarrays.
Authors:Chirayil S, Chirayil R, Luebke KJ
Journal:Nucleic Acids Res
PubMed ID:19561197
We have screened peptoid microarrays to identify specific ligands for the RNA hairpin precursor of miR-21, a microRNA involved in cancer and heart disease. Microarrays were printed by spotting a library of 7680 N-substituted oligoglycines (peptoids) onto glass slides. Two compounds on the array specifically bind RNA having the sequence ... More
Interaction with the 5D3 monoclonal antibody is regulated by intramolecular rearrangements but not by covalent dimer formation of the human ABCG2 multidrug transporter.
Authors:Ozvegy-Laczka C, Laczkó R, Hegedus C, Litman T, Várady G, Goda K, Hegedus T, Dokholyan NV, Sorrentino BP, Váradi A, Sarkadi B
Journal:J Biol Chem
PubMed ID:18644784
Human ABCG2 is a plasma membrane glycoprotein working as a homodimer or homo-oligomer. The protein plays an important role in the protection/detoxification of various tissues and may also be responsible for the multidrug-resistant phenotype of cancer cells. In our previous study we found that the 5D3 monoclonal antibody shows a ... More