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引用和文献 (23)
Invitrogen™
BODIPY™ FL 哌唑嗪
哌唑嗪是 a1-肾上腺素能受体的高亲和力拮抗剂。绿色荧光 BODIPY™ FL 哌唑嗪衍生物可用于定位并检测 a1-肾上腺素能受体。了解更多信息
| 货号 | 数量 |
|---|---|
| B7433 | 100 μg |
货号 B7433
价格（CNY)
4,495.00
Each
数量:
100 μg
价格（CNY)
4,495.00
Each
哌唑嗪是 a1-肾上腺素能受体的高亲和力拮抗剂。绿色荧光 BODIPY™ FL 哌唑嗪衍生物可用于定位并检测 a1-肾上腺素能受体。
仅供科研使用。不可用于诊断程序。
规格
标签类型BODIPY 染料
分子式C28H32BF2N7O3
产品线BODIPY
数量100 μg
建议的储存条件在冷冻冰箱（-5°C 至 -30°C）中避光储存。
运输条件室温
产品类型FL 哌唑嗪
Unit SizeEach
引用和文献 (23)
引用和文献
Abstract
Evidence for two nonidentical drug-interaction sites in the human P-glycoprotein.
Journal:Proc Natl Acad Sci U S A
PubMed ID:9380680
'Human P-glycoprotein (Pgp) confers multidrug resistance to cancer cells by ATP-dependent extrusion of a great many structurally dissimilar hydrophobic compounds. The manner in which Pgp recognizes these different substrates is unknown. The protein shows internal homology between its N- and C-terminal halves, each comprised of six putative transmembrane helices and
Multidrug transporter activity in lymphocytes.
Journal:Br J Pharmacol
PubMed ID:15492020
'Multidrug transporters play a dual role in haematopoietic cells, mediating the efflux of xenobiotics and regulating cell migration. For several reasons including the lack of specific antibodies, reports of multidrug transporter distribution on lymphocytes conflict. Murine B cells have been reported to completely lack transporter activity. Through analysis of parental
Release of amines from acidified stores following accumulation by Transport-P.
Journal:Br J Pharmacol
PubMed ID:11181426
'1. Transport-P is an uptake process for amines in peptidergic neurones of the hypothalamus. It differs from other uptake processes by its anatomical location in post-synaptic neurones, its functional properties and by the structure of its ligands. Transport-P accumulates amines in intracellular vesicles, derives its energy from the electrochemical proton
Visual detection of transport-P in peptidergic neurones.
Journal:Br J Pharmacol
PubMed ID:9138694
'1. Hypothalamic peptidergic neurones possess an uptake process for amines (transport-P), for which prazosin is a substrate. It is characterized by a paradoxical increase in the accumulation of [3H]-prazosin when the concentration of unlabelled prazosin is increased above 10(-7) M. This increase is due to activation of a proton-dependent, vacuolar-type
Pharmacological implications of cellular localization of alpha1-adrenoceptors in native smooth muscle cells.
Journal:J Auton Pharmacol
PubMed ID:10961735
'1. This study examines the cellular localization of alpha1-adrenoceptors and demonstrates that binding to intracellular receptive binding sites in native smooth muscle cells may influence the pharmacological profile of agonists or antagonists. The example tissue studied was rat basilar artery. 2. An alpha1-adrenoceptor antagonist and fluorescent analogue of prazosin, BODIPY-FL