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引用和文献 (22)
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DiFMUP（6,8-二氟-4-甲基伞形酮磷酸酯）
DiFMUP 是一种氟化的 4-甲基伞形酮磷酸酯 (MUP) 衍生物，其 pKa 低于 MUP，这使得 DiFMUP 成为在低了解更多信息
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| 货号 | 数量 |
|---|---|
| D22065 | 10 x 10mg |
| D6567 | 5mg |
货号 D22065
价格（CNY)
35,799.00
Each
数量:
10 x 10mg
价格（CNY)
35,799.00
Each
DiFMUP 是一种氟化的 4-甲基伞形酮磷酸酯 (MUP) 衍生物，其 pKa 低于 MUP，这使得 DiFMUP 成为在低 pH 值条件下持续测定酸性磷酸酶的绝佳底物。DiFMUP 反应产物的最大激发/发射波长为 ∼358/450 nm。DiFMUP 还具有十瓶包装，每个小瓶 10 mg (D-22065)。
仅供科研使用。不可用于诊断程序。
规格
颜色蓝色
激发/发射358⁄455
适用于（设备）微孔板读数仪
标签或染料DiFMU
数量10 x 10mg
运输条件室温
底物磷酸酶底物
检测方法荧光
形式粉末
底物属性化学底物
目标酶磷酸酶
Unit SizeEach
内容与储存
在冰箱（-5 至 -30°C）中储存。
引用和文献 (22)
引用和文献
Abstract
Surface phosphophilicity of aluminum-containing adjuvants probed by their efficiency for catalyzing the P--O bond cleavage with chromogenic and fluorogenic substrates.
Journal:Anal Biochem
PubMed ID:11476547
'Aluminum-containing adjuvants are widely used in a variety of vaccine products, such as recombinant proteins, virus-like particles, conjugated polysaccharides, and recently DNA vaccines. Aluminum-containing adjuvants are also known to have a high affinity to inorganic phosphate and its mono- or diesters. Since phosphate groups are present in many antigens as
Negative regulation of EGFR signalling through integrin-alpha1beta1-mediated activation of protein tyrosine phosphatase TCPTP.
Journal:Nat Cell Biol
PubMed ID:15592458
'Integrin-mediated cell adhesion regulates a multitude of cellular responses, including proliferation, survival and cross-talk between different cellular signalling pathways. So far, integrins have been mainly shown to convey permissive signals enabling anchorage-dependent receptor tyrosine kinase signalling. Here we show that a collagen-binding integrin alpha(1)beta(1) functions as a negative regulator of
Discovery of a novel shp2 protein tyrosine phosphatase inhibitor.
Journal:Mol Pharmacol
PubMed ID:16717135
'Shp2 is a nonreceptor protein tyrosine phosphatase (PTP) encoded by the PTPN11 gene. It is involved in growth factorinduced activation of mitogen-activated protein (MAP) kinases Erk1 and Erk2 (Erk1/2) and has been implicated in the pathogenicity of the oncogenic bacterium Helicobacter pylori. Moreover, gain-of-function Shp2 mutations have been found in
Loss of phosphatase activity in Ptp69D alleles supporting axon guidance defects.
Journal:J Cell Biochem
PubMed ID:16514605
'PTP69D is a receptor protein tyrosine phosphatase that was identified as a key regulator of neuromuscular axon guidance in Drosophila, and has subsequently been shown to play a similar role in the central nervous system and retina. Three Ptp69D alleles with mutations involving catalytically important residues exhibit a high degree
High yield expression of serine/threonine protein phosphatase type 5, and a fluorescent assay suitable for use in the detection of catalytic inhibitors.
Journal:Assay Drug Dev Technol
PubMed ID:17939754
'Protein phosphatase type 5 (PP5) belongs to the PPP family of serine/threonine protein phosphatases and is expressed in most, if not all, human tissues. Although the physiological roles played by PP5 are not yet clear, PP5 is found in association with several proteins that influence intracellular signaling networks initiated by