Sodium orthovanadate, 100mM aq. soln.
Sodium orthovanadate, 100mM aq. soln.
Sodium orthovanadate, 100mM aq. soln.
Thermo Scientific Chemicals

Sodium orthovanadate, 100mM aq. soln.

CAS: 13721-39-6 | Na3O4V | 183.907 g/mol
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数量:
50 mL
100 mL
货号 J60191.AE
又称 J60191-AE
价格(CNY)
-
数量:
100 mL
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规格
CAS13721-39-6
ChEBICHEBI:35607
化学名称或材料Sodium orthovanadate
颜色Colorless
浓度或成分(按分析物或组分)100mM aq. soln.
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Sodium orthovanadate, is used as an inhibitor of several phosphatases and kinases such as protein tyrosine phosphatases (PTPs), alkaline phosphatase (ALP), and ATPase. It also acts as an inhibitor of adenosine kinase (AK) and phosphofructokinase (PFK). It also suppresses p53-mediated apoptosis by transcription-dependent and -independent pathways.

This Thermo Scientific Chemicals brand product was originally part of the Alfa Aesar product portfolio. Some documentation and label information may refer to the legacy brand. The original Alfa Aesar product / item code or SKU reference has not changed as a part of the brand transition to Thermo Scientific Chemicals.

Applications
Sodium orthovanadate, is used as an inhibitor of several phosphatases and kinases such as protein tyrosine phosphatases (PTPs), alkaline phosphatase (ALP), and ATPase. It also acts as an inhibitor of adenosine kinase (AK) and phosphofructokinase (PFK). It also suppresses p53-mediated apoptosis by transcription-dependent and -independent pathways.

Solubility
It is soluble in water (50 mg/ml, )

Notes
Store in cool place. Keep container tightly closed in a dry and well-ventilated place. Keep away fom strong oxidizing agents.
RUO – Research Use Only

General References:

  1. Ai et al. Inhibition of small-intestinal sugar absorption mediated by sodium orthovanadate Na3VO4 in rats and its mechanisms. World J.Gastroenterol. 2004, 15,(24), 3612-5.
  2. Matsumoto et al. Sodium orthovanadate enhances proliferation of progenitor cells in the adult rat subventricular zone after focal cerebral ischemia. J.Pharmacol.Exp.Ther. 2006, 318,(3), 982-91.

常见问题解答 (FAQ)

Is Sodium orthovanadate, 100 mM aq. soln. (Cat. No. J60191.xx) activated?

Sodium orthovanadate, 100mM aq. soln. (Cat. No. J60191.xx) is activated and suitable for use as a phosphatase inhibitor. Activation was achieved by boiling and adjusting the pH to 10.0.