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Thermo Scientific Chemicals
1H-Tetrazole, 0.45M in acetonitrile
Coupling reagent for preparation of polynucleotides | CAS: 288-94-8 | CH2N4 | 70.055 g/mol
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化学标识符
CAS288-94-8
IUPAC Name2H-1,2,3,4-tetrazole
Molecular FormulaCH2N4
InChI KeyKJUGUADJHNHALS-UHFFFAOYSA-N
SMILESN1N=CN=N1
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规格
规格表
规格表Appearance (Color)Clear colorless
FormLiquid
Water Content (Karl Fischer Titration)≤ 60 ppm
CommentFiltered under argon through a 0.2micron filter
Concentration0.45 - 0.50M tetrazole in acetonitrile
1H-Tetrazole is used as a bioisostere for the carboxylate group. It is also used as coupling reagent for preparation of polynucleotides.
This Thermo Scientific Chemicals brand product was originally part of the Alfa Aesar product portfolio. Some documentation and label information may refer to the legacy brand. The original Alfa Aesar product / item code or SKU reference has not changed as a part of the brand transition to Thermo Scientific Chemicals.
Applications
1H-Tetrazole is used as a bioisostere for the carboxylate group. It is also used as coupling reagent for preparation of polynucleotides.
Solubility
Miscible with water.
Notes
Incompatible with reducing agents and alkali metals.
1H-Tetrazole is used as a bioisostere for the carboxylate group. It is also used as coupling reagent for preparation of polynucleotides.
Solubility
Miscible with water.
Notes
Incompatible with reducing agents and alkali metals.
RUO – Research Use Only
General References:
- Frija, L. M. T A.; Ismael, A.; Cristiano, M. L. S. Photochemical Transformations of Tetrazole Derivatives: Applications in Organic Synthesis. Molecules 2010, 15 (5), 3757-3774.
- Dabbagh, A. H.; Mansoori, Y. New azoic dyes containing (1H)-tetrazole and azido group. Dyes Pigm. 2002, 54 (1), 37-46.