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beta-Nicotinamide adenine dinucleotide phosphate reduced tetrasodium salt, 95%
CAS: 2646-71-1 | C21H26N7Na4O17P3 | 833.35 g/mol
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化学标识符
CAS2646-71-1
IUPAC Nametetrasodium [(2R,3R,4R,5R)-5-(6-amino-9H-purin-9-yl)-3-hydroxy-4-(phosphonatooxy)oxolan-2-yl]methyl ({[(2R,3S,4R,5R)-5-(3-carbamoyl-1,4-dihydropyridin-1-yl)-3,4-dihydroxyoxolan-2-yl]methyl phosphonato}oxy)phosphonate
Molecular FormulaC21H26N7Na4O17P3
InChI KeyWYWWVJHQDVCHKF-NRTBITFTNA-J
SMILES[Na+].[Na+].[Na+].[Na+].NC(=O)C1=CN(C=CC1)[C@@H]1O[C@H](COP([O-])(=O)OP([O-])(=O)OC[C@H]2O[C@H]([C@H](OP([O-])([O-])=O)[C@@H]2O)N2C=NC3=C(N)N=CN=C23)[C@@H](O)[C@H]1O
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规格
规格表
规格表Appearance (Color)Light cream to yellow
FormCrystalline powder
Assay (HPLC)≥ 95.0%
Water Content (Karl Fischer Titration)≤ 8.0%
Solution TestClear solution (50 mg/ml in water)
NADPH tetra sodium salt is used as an ubiquitous cofactor and biological reducing agent. β-NADPH is a coenzyme found in all living cells and is involved in redox reactions carrying electrons from one reaction to another. It is used as an electron donor, cofactor for many redox enzymes including nitric oxide synthetase.
This Thermo Scientific Chemicals brand product was originally part of the Alfa Aesar product portfolio. Some documentation and label information may refer to the legacy brand. The original Alfa Aesar product / item code or SKU reference has not changed as a part of the brand transition to Thermo Scientific Chemicals.
Applications
NADPH tetra sodium salt is used as an ubiquitous cofactor and biological reducing agent. β-NADPH is a coenzyme found in all living cells and is involved in redox reactions carrying electrons from one reaction to another. It is used as an electron donor, cofactor for many redox enzymes including nitric oxide synthetase.
Solubility
Soluble in water (50 mg/ml).
Notes
Store in cool place. Keep container tightly closed in a dry and well-ventilated place. Recommended storage temperature -20°C. Light sensitive. Keep away from strong oxidizing agents.
NADPH tetra sodium salt is used as an ubiquitous cofactor and biological reducing agent. β-NADPH is a coenzyme found in all living cells and is involved in redox reactions carrying electrons from one reaction to another. It is used as an electron donor, cofactor for many redox enzymes including nitric oxide synthetase.
Solubility
Soluble in water (50 mg/ml).
Notes
Store in cool place. Keep container tightly closed in a dry and well-ventilated place. Recommended storage temperature -20°C. Light sensitive. Keep away from strong oxidizing agents.
RUO – Research Use Only
General References:
- D Gallego.; V Gil.; J Aleu. Pharmacological characterization of purinergic inhibitory neuromuscular transmission in the human colon. Neurogastroenterology & Motility. 2011, 23, (8), 792-e338.
- V Gil.; M Martínez-Cutillas.; N Mane. P2Y1 knockout mice lack purinergic neuromuscular transmission in the antrum and cecum. Neurogastroenterology & Motility. 2013, 25, (3), e170-e182.