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Thermo Scientific Chemicals
Ketotifen fumarate, 99%
CAS: 34580-14-8 | C23H23NO5S | 425.499 g/mol
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化学标识符
CAS34580-14-8
IUPAC Name(2E)-but-2-enedioic acid; 2-(1-methylpiperidin-4-ylidene)-6-thiatricyclo[8.4.0.0³,⁷]tetradeca-1(14),3(7),4,10,12-pentaen-8-one
Molecular FormulaC23H23NO5S
InChI KeyYNQQEYBLVYAWNX-WLHGVMLRSA-N
SMILESOC(=O)C=CC(O)=O.CN1CCC(CC1)=C1C2=C(SC=C2)C(=O)CC2=CC=CC=C12
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规格
规格表
规格表Assay from Supplier's CofA≥98.5%
Appearance (Color)White to pale cream to pale yellow
FormPowder
Mass SpecConforms to structure
Ketotifen fumaratin is an H1 receptor antagonist. In its ophthalmic form, it is used to treat allergic conjunctivitis, or the itchy red eyes caused by allergies.
This Thermo Scientific Chemicals brand product was originally part of the Alfa Aesar product portfolio. Some documentation and label information may refer to the legacy brand. The original Alfa Aesar product / item code or SKU reference has not changed as a part of the brand transition to Thermo Scientific Chemicals.
Solubility
Soluble in water (10 mg/ml), DMSO (100 mM), and methanol.
Notes
Store in cool place. Keep container tightly closed in a dry and well-ventilated place. Store away from strong oxidizing agents.
Soluble in water (10 mg/ml), DMSO (100 mM), and methanol.
Notes
Store in cool place. Keep container tightly closed in a dry and well-ventilated place. Store away from strong oxidizing agents.
RUO – Research Use Only
General References:
- MD Gregg J. Berdycorrespondence,; MD Dennis L. Spangler,; MD George Bensch,; MD Susan S. Berdy,; OD Robert C. Brusatti. A comparison of the relative efficacy and clinical performance of olopatadine hydrochloride 0.1% ophthalmic solution and ketotifen fumarate 0.025% ophthalmic solution in the conjunctival antigen challenge model. Clinical therapeutics. 2000, 22 (7), 826-833.
- Mayank Joshi,; Ambikanandan Misra.Dry powder inhalation of liposomal Ketotifen fumarate: formulation and characterization. International Journal of Pharmaceutics. 2001, 223 (1-2).