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2-Chloroadenosine
CAS: 146-77-0 | C10H12ClN5O4 | 301.69 g/mol
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化学标识符
CAS146-77-0
IUPAC Name(2R,3R,4S,5R)-2-(6-amino-2-chloro-9H-purin-9-yl)-5-(hydroxymethyl)oxolane-3,4-diol
Molecular FormulaC10H12ClN5O4
InChI KeyBIXYYZIIJIXVFW-SBTUYZBDNA-N
SMILESNC1=C2N=CN([C@@H]3O[C@H](CO)[C@@H](O)[C@H]3O)C2=NC(Cl)=N1
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规格
规格表
规格表FormPowder or crystalline powder
Identification (FTIR)Conforms
Appearance (Color)White to pale cream
Assay from Supplier's CofA≥98.5% (HPLC)
2-Chloroadenosine is used as a selective A1-adenosine receptor agonist, and also Induces apoptosis.
This Thermo Scientific Chemicals brand product was originally part of the Alfa Aesar product portfolio. Some documentation and label information may refer to the legacy brand. The original Alfa Aesar product / item code or SKU reference has not changed as a part of the brand transition to Thermo Scientific Chemicals.
Applications
2-Chloroadenosine is used as a selective A1-adenosine receptor agonist, and also Induces apoptosis.
Solubility
Soluble in water.
Notes
protect from heat. Store away from oxidizing agents.
2-Chloroadenosine is used as a selective A1-adenosine receptor agonist, and also Induces apoptosis.
Solubility
Soluble in water.
Notes
protect from heat. Store away from oxidizing agents.
RUO – Research Use Only
General References:
- Evans, M.C.; Swan, J.H.; Meldrum, B.S. An adenosine analogue, 2-chloroadenosine, protects against long term development of ischaemic cell loss in the rat hippocampus. Neuroscience Letters. 1987, 83, (3), 287-292.
- Haslam, R.J.; Lynham, J.A. Activation and inhibition of blood platelet adenylate cyclase by adenosine or by 2-chloroadenosine. Life Sciences. 1972, 11, (23), 1143-1154.