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Thermo Scientific Chemicals
Azadibenzocyclooctyne acid
CAS: 1425485-72-8 | C21H19NO3 | 333.39 g/mol
| 货号 | 数量 |
|---|---|
| J64549.MB 又称 J64549-MB | 25 mg |
规格
CAS1425485-72-8
化学名称或材料Azadibenzocyclooctyne acid
颜色White to Gray
化学式量333.38
健康危害 1H315-H319-H335
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Azadibenzocyclooctyne acid is the simplest amine reactive reagent for introducing a dibenzylcyclooctyne to available amine functionality.Azadibenzocyclooctyne acid is widely useful in strain-promoted copper-free azide-alkyne click chemistry reactions. It reacts with azide functionalized compounds or bimolecules to give stable triazole linkage without a need for a Cu(I) catalyst.
This Thermo Scientific Chemicals brand product was originally part of the Alfa Aesar product portfolio. Some documentation and label information may refer to the legacy brand. The original Alfa Aesar product / item code or SKU reference has not changed as a part of the brand transition to Thermo Scientific Chemicals.
Applications
Azadibenzocyclooctyne acid is the simplest amine reactive reagent for introducing a dibenzylcyclooctyne to available amine functionality.Azadibenzocyclooctyne acid is widely useful in strain-promoted copper-free azide-alkyne click chemistry reactions. It reacts with azide functionalized compounds or bimolecules to give stable triazole linkage without a need for a Cu(I) catalyst.
Solubility
Soluble in dimethyl sulfoxide and dimethyl formamide.
Notes
Store in cool place. Incompatible with amines.
Azadibenzocyclooctyne acid is the simplest amine reactive reagent for introducing a dibenzylcyclooctyne to available amine functionality.Azadibenzocyclooctyne acid is widely useful in strain-promoted copper-free azide-alkyne click chemistry reactions. It reacts with azide functionalized compounds or bimolecules to give stable triazole linkage without a need for a Cu(I) catalyst.
Solubility
Soluble in dimethyl sulfoxide and dimethyl formamide.
Notes
Store in cool place. Incompatible with amines.
RUO – Research Use Only
General References:
- Patterson, D. M.; Prescher, J. A. Orthogonal bioorthogonal chemistries. Curr. Opin. Chem. Biol. 2015, 28, 141-149.
- Jung, S.; Yi, H. Integrated fabrication-conjugation approaches for biomolecular assembly and protein sensing with hybrid microparticle platforms and biofabrication - A focused minireview. Korean J. Chem. Eng. 2015, 32 (9), 1713-1719.