NeuroTrace™ 640/660 深红色荧光尼氏染色剂 - DMSO 溶液
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NeuroTrace™ 640/660 深红色荧光尼氏染色剂 - DMSO 溶液
引用和文献 (20)
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NeuroTrace™ 640/660 深红色荧光尼氏染色剂 - DMSO 溶液

尼氏染色是一种标准组织学方法，用于显示脑和脊髓中的神经元。尼氏物质由神经元核周体和树突中与粗面内质网相关的核糖体 RNA 组成，在损伤或再生神经元的细胞体内再分布，为神经元的生理状态提供标志物。我们的 NeuroTrace 640/660 深红色荧光尼氏染色剂对神经元的尼氏物质特征具有选择性，并且与甲苯胺蓝或甲酚紫等传统组织学染料相比，其灵敏度更高。了解更多信息
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货号数量
N214831 mL
货号 N21483
价格（CNY)
2,858.00
Online Exclusive
Ends: 31-Dec-2025
3,873.00
共减 1,015.00 (26%)
Each
添加至购物车
数量:
1 mL
价格（CNY)
2,858.00
Online Exclusive
Ends: 31-Dec-2025
3,873.00
共减 1,015.00 (26%)
Each
添加至购物车
尼氏染色是一种标准组织学方法，用于显示脑和脊髓中的神经元。尼氏物质由神经元核周体和树突中与粗面内质网相关的核糖体 RNA 组成，在损伤或再生神经元的细胞体内再分布，为神经元的生理状态提供标志物。我们的 NeuroTrace 640/660 深红色荧光尼氏染色剂对神经元的尼氏物质特征具有选择性，并且与甲苯胺蓝或甲酚紫等传统组织学染料相比，其灵敏度更高。
仅供科研使用。不可用于诊断程序。
规格
颜色Deep Red
检测方法荧光
适用于（设备）荧光显微镜
产品类型尼氏染色
数量1 mL
运输条件室温
子细胞定位尼氏体
激发/发射640/660 nm
产品线NEUROTRACE
Unit SizeEach
内容与储存
储存在冰箱（-5 至 -30°C）中并避光。

常见问题解答 (FAQ)

我可以使用NeuroTrace Nissl 染色剂染色胶质或其他类型细胞，该如何改善染色效果，使其对神经元的选择性更强？

我们的NeuroTrace Nissl 染色剂可标记Nissl底物——该底物由与粗面内质网相关的核糖体RNA构成，并大量存在于神经元中。这些染料并非完全特异性靶向神经元，但由于神经元蛋白质的合成水平高而对神经元选择性染色。在某些情况下它们可能会对其他类型细胞（如神经胶质细胞）染色，所以你可能需要降低染色浓度以获得更具选择性的神经元标记效果。对于神经元染色，我们建议的稀释范围是20到300倍。

NeuroTrace Nissl染色剂可染色石蜡切片吗？

我们只在小鼠脑冰冻切片上测试过，但是有文献指出NeuroTrace Nissl 染色剂可染色石蜡切片。

NeuroTrace Nissl 染色剂是什么?

这些染料是保密的，但它们是标记Nissl物质的染色剂。Nissl物质由与粗面内质网相关的核糖体RNA构成，并大量存在于神经元细胞中。 

你们有哪些神经元示踪产品？

详细信息请查阅此网页（https://www.thermofisher.com/us/en/home/life-science/cell-analysis/cell-tracing-tracking-and-morphology/neuronal-tracing.html）。

I am labeling brain cryosections with a NeuroTrace Nissl Stain. Is this compatible with antibody labeling?

Yes. We have done this successfully with an anti-GFAP primary and an Alexa Fluor secondary antibody. We would recommend labeling with the primary and secondary antibodies first, then following up with the standard NeuroTrace Nissl Stain protocol.

Find additional tips, troubleshooting help, and resources within our Cell Analysis Support Center.

View all NeuroTrace™ 640/660 深红色荧光尼氏染色剂 - DMSO 溶液 FAQs

引用和文献 (20)

引用和文献
Abstract
Glutamate acting on AMPA but not NMDA receptors modulates the migration of hippocampal interneurons.
Authors:Manent JB, Jorquera I, Ben-Ari Y, Aniksztejn L, Represa A,
Journal:J Neurosci
PubMed ID:16738232
'Paracrine GABA and glutamate acting, respectively, on GABAA and NMDA receptors modulate the migration of hippocampal pyramidal cells. Using corticohippocampal organotypic explants from glutamic acid decarboxylase (GAD) 67-enhanced green fluorescent protein (EGFP) knock-in embryos, we now report that, in contrast to pyramidal neurons, the blockade of AMPA but not NMDA ... More
Differential roles of the dopamine 1-class receptors, D1R and D5R, in hippocampal dependent memory.
Authors:Sariñana J, Kitamura T, Künzler P, Sultzman L, Tonegawa S,
Journal:
PubMed ID:24843151
'Activation of the hippocampal dopamine 1-class receptors (D1R and D5R) are implicated in contextual fear conditioning (CFC). However, the specific role of the D1R versus D5R in hippocampal dependent CFC has not been investigated. Generation of D1R- and D5R-specific in situ hybridization probes showed that D1R and D5R mRNA expression ... More
Phenotypic heterogeneity and plasticity of isocortical and hippocampal astrocytes in the human brain.
Authors:Sosunov AA, Wu X, Tsankova NM, Guilfoyle E, McKhann GM, Goldman JE,
Journal:
PubMed ID:24501367
'To examine the diversity of astrocytes in the human brain, we immunostained surgical specimens of temporal cortex and hippocampus and autopsy brains for CD44, a plasma membrane protein and extracellular matrix receptor. CD44 antibodies outline the details of astrocyte morphology to a degree not possible with glial fibrillary acidic protein ... More
Neutralization of Nogo-A enhances synaptic plasticity in the rodent motor cortex and improves motor learning in vivo.
Authors:Zemmar A, Weinmann O, Kellner Y, Yu X, Vicente R, Gullo M, Kasper H, Lussi K, Ristic Z, Luft AR, Rioult-Pedotti M, Zuo Y, Zagrebelsky M, Schwab ME,
Journal:
PubMed ID:24966370
The membrane protein Nogo-A is known as an inhibitor of axonal outgrowth and regeneration in the CNS. However, its physiological functions in the normal adult CNS remain incompletely understood. Here, we investigated the role of Nogo-A in cortical synaptic plasticity and motor learning in the uninjured adult rodent motor cortex. ... More
Superficially projecting principal neurons in layer V of medial entorhinal cortex in the rat receive excitatory retrosplenial input.
Authors:Czajkowski R, Sugar J, Zhang SJ, Couey JJ, Ye J, Witter MP,
Journal:
PubMed ID:24089485
Principal cells in layer V of the medial entorhinal cortex (MEC) have a nodal position in the cortical-hippocampal network. They are the main recipients of hippocampal output and receive inputs from several cortical areas, including a prominent one from the retrosplenial cortex (RSC), likely targeting basal dendrites of layer V ... More
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