A phospho specific antibody directed to the ezrin⁄radixin⁄moesin (ERM) peptide that is a substrate for LRRK2 (Leucine-rich repeat kinase 2) and LRRK2 mutants. Mutations in LRRK2 have been found to be related to late-onset Parkinson's disease. For use in combination with the Fluorescein-ERM (LRRKtide) substrate (PV4901) to evaluate inhibitors in medium to high throughput screening applications.
For Research Use Only. Not for use in diagnostic procedures.
规格
偶联物
Tb (Terbium)/Lanthanide Chelates
数量
25 μg
激发/发射
340⁄490, 520
反应性
Human
运输条件
Dry Ice
读值
End Point
反应性 abrv
Hu
靶标基因
Ser/Thr Kinases
产品线
LanthaScreen™
内容与储存
Terbium-labeled pERM (pLRRKtide) antibody in HEPES buffered saline. Store at -20°C.