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A general reagent to monitor tyrosine kinase activity, the PY20 antibody binds to phosphorylated tyrosines within a peptide or physiological protein substrate. For use in combination with AlexaFluor 647-poly-GT (PV5693) to evaluate inhibitors in medium to high throughput screening applications.
For Research Use Only. Not for use in diagnostic procedures.
规格
抗原
Tyrosine kinases
应用
Kinase Assay, Kinase Assay
浓度
0.53mg/mL
偶联物
Europium
抗原分子量
150kDa
数量
25 μg
调控状态
RUO, RUO
研究学科
Pharma and Biopharma
首要或次要
Primary
包装
1 Kit(s)
检测条目
Biochemical europium phospho-specific activity
检测方法
Fluorescent
激发/发射
340⁄615
运输条件
Dry Ice
目标条目
ABL1 G250E, CSF1R, CSK, EPHA5, KIT, PDGFRA V561D, SYK, TYRO3, ZAP70, FGFR1, FGFR2, EGFR, EPHB2, FGFR4, IGF1R, LYNA, MATK, MERTK, NTRK3, RET V804L, TEK, FLT1, MUSK, SRCN1, ABL1 E255K, EPHA4, FYN, PTK2, PTK2B, RET, ABL1 T315I, EPHA3, EPHB4, FLT3, FLT4, INSR, LCK, YES1, EGFR L858R, ERBB4, KDR, MET, TNK2, ABL1, ABL2, AXL, FGFR3, FGR, HCK, KIT V654A, EPHA1, EPHA8, EPHB3, INSRR, LYNB, NTRK1, PDGFRA D842V, SRMS, EGFR L861Q, EPHA2, FER, LTK, PDGFRA, EPHA7, EPHB1, FRK, ITK, FLT3 D835Y, SRC, BTK, FES, ERBB2, NTRK2
技术
TR-FRET
已验证激酶
EGFR
产品线
LanthaScreen™
内容与储存
Europium-labeled anti-PY20 antibody is supplied in HEPES-buffered saline. Store at -20°C.
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