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Invitrogen
Bcl-10 Monoclonal Antibody (151)
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产品信息
MA1-20160
应用
建议稀释比
已发表文章
产品规格
宿主/亚型
Mouse
/ IgG1
分类
Monoclonal
类型
Antibody
克隆号
151
抗原
Recombinant, full length, human Bcl10 protein.
偶联物
形式
Liquid
浓度
2.1 mg/mL
保存条件
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
运输条件
Wet ice
RRID
产品详细信息
MA1-20160 detects Bcl10 in human samples.
MA1-20160 has been successfully used in ELISA, immunohistochemistry (paraffin) and Western blot procedures.
The MA1-20160 immunogen is recombinant, full length, human Bcl10 protein.
靶标信息
BCL-10 is an N-terminal CARD (Caspase Recruitment Domain) containing protein that is involved in the adaptive immune response. It promotes apoptosis, pro-caspase-9 maturation, and activation of NF-kappa-B via NIK and IKK. BCL-10 is also an adapter protein between upstream TNFR1-TRADD-RIP complex and the downstream NIK-IKK-IKAP complex. It is a substrate for MALT1. Mutations in the gene can lead to Immmunodeficiency 37 or Lymphoma, mucosa-associated lymphoid type.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
