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Invitrogen
Phospho-PAK1/2/3 (Ser141) Polyclonal Antibody
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Phospho-PAK1/2/3 (Ser141) Antibody (44-940G) in WB
Western blot analysis was performed on whole cell extracts (30 µg lysate) of SH-SY5Y (Lane 1), SH-SY5Y treated with 100 uM Pervanadate for 1 hour (Lane 2), HeLa (Lane 3), HeLa treated with 100 uM Pervanadate for 1 hour (Lane 4), K562 (Lane 5), K562 treated with 100 uM Pervanadate for 1 hour (Lane 6). The blots were probed with Anti-Phospho-PAK1 + 2 + 3 pSer141 Rabbit Polyclonal Antibody (Product # 44-940G, ... View More
Please note: We are reviewing Western blot images included in the antibody testing data in our catalog, including those provided by third parties. Unless expressly labeled or annotated as “raw-unedited”, Western blot images included in the antibody testing data in our catalog may have been edited, optimized or otherwise adjusted for presentation.
产品信息
44-940G
应用
建议稀释比
已发表文章
产品规格
种属反应
Human
已发表种属
Bovine,
Human,
Mouse,
Rat
宿主/亚型
Rabbit
/ IgG
分类
Polyclonal
类型
Antibody
抗原
Synthetic phosphopeptide derived from a region of human PAK2 containing serine 141. The sequence is conserved in rat and rabbit.
偶联物
Unconjugated
Unconjugated
Unconjugated
形式
Liquid
纯化类型
Antigen affinity chromatography
保存液
Dulbecco's PBS, pH 7.3, with 1mg/mL BSA
内含物
0.05% sodium azide
保存条件
-20°C
运输条件
Ambient (domestic); Wet ice (international)
RRID
靶标信息
In mammals, there are several identified isoforms of p21-Activated Protein Kinases or PAKs: alpha-PAK (also known as PAK-1) and beta-PAK (also known as PAK-3) are mostly brain-specific, while gamma-PAK (also known as PAK-2) is expressed ubiquitously (Jakobi et al., 2003). Mutations of the gene coding for PAK-3 are associated wit X-linked mental retardation and recent work indicates that PAK-3 is a key regulator of synapse formation and plasticity in the hippocampus (Boda et al., 2004). PAK-3 is thought to play a key role in regulation of cell shape and motility as well as cell death (Jakobi et al., 2003; Walter et al., 1998). Autophosphorylation of Thr402 in the protein has been found to be essential for activation of PAK (Jakobi et al., 2000).
仅用于科研。不用于诊断过程。未经明确授权不得转售。
生物信息学
蛋白别名: ADRB2; Alpha-PAK; aPAK; Beta-PAK; BPAK; CDKN1A; CLAP; EC 2.7.11.1; gamma pak; Gamma-PAK; hPAK3; kinase PAK1; Oligophrenin-3; p21-activated kinase 1; p21-activated kinase 2; p21-activated kinase 3; p58; p65-PAK; PAK 1; PAK alpha; PAK beta; PAK gamma; PAK-1; PAK-2; PAK-3; PAK-a; PAK-B; PAK-y; PAK65; S6/H4 kinase; Serine/threonine-protein kinase PAK 1; Serine/threonine-protein kinase PAK 2; Serine/threonine-protein kinase PAK 3; yPAK
基因别名: OPHN3; PAK1; PAK2; PAK3
Entrez Gene ID: (Human) 5058, (Human) 5062, (Human) 5063
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