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NeoBiotechnologies
NR5A2/LRH1 Monoclonal Antibody (PCRP-NR5A2-1B8)
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Please note: We are reviewing Western blot images included in the antibody testing data in our catalog, including those provided by third parties. Unless expressly labeled or annotated as “raw-unedited”, Western blot images included in the antibody testing data in our catalog may have been edited, optimized or otherwise adjusted for presentation.
产品信息
2494-MSM2-P1
应用
建议稀释比
已发表文章
产品规格
种属反应
Human
宿主/亚型
Mouse
/ IgG2b
分类
Monoclonal
类型
Antibody
克隆号
PCRP-NR5A2-1B8
抗原
Recombinant human NR5A2 protein
偶联物
Unconjugated
Unconjugated
Unconjugated
形式
Liquid
浓度
200 µg/mL
规格
100 µg
纯化类型
Protein A/G
保存液
PBS with 0.05% BSA
内含物
0.05% sodium azide
保存条件
4°C
运输条件
Ambient (domestic); Wet ice (international)
产品详细信息
Positive Control:HeLa or MCF-7 cells.
Cellular Location: Nucleus.
靶标信息
Binds to the sequence element 5'-AACGACCGACCTTGAG-3' of the enhancer II of hepatitis B virus genes, a critical cis-element of their expression and regulation. May be responsible for the liver-specific activity of enhancer II, probably in combination with other hepatocyte transcription factors. Key regulator of cholesterol 7-alpha-hydroxylase gene (CYP7A) expression in liver. May also contribute to the regulation of pancreas-specific genes and play important roles in embryonic development.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
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生物信息学
蛋白别名: b1-binding factor, hepatocyte transcription factor which activates enhancer II of hepatitis B virus; CYP7A promoter-binding factor; fetoprotein-alpha 1 (AFP) transcription factor; FTF; FTF; similar to nuclear hormone receptor; FTZ F1; FTZ F1beta; hB1F 2; hepatocytic transcription factor hB1F-3; live; nuclear receptor; similar to FTZ-F1; orphan nuclear receptor; unnamed protein product
基因别名: B1F; B1F2; CPF; FTF; FTZ-F1; FTZ-F1beta; hB1F-2; LRH-1; LRH1
UniProt ID: (Human) O00482
Entrez Gene ID: (Human) 2494
transcription regulatory region sequence-specific DNA binding
RNA polymerase II core promoter proximal region sequence-specific DNA binding
RNA polymerase II transcription factor activity, sequence-specific DNA binding
transcription cofactor binding
DNA binding
chromatin binding
double-stranded DNA binding
transcription factor activity, sequence-specific DNA binding
RNA polymerase II transcription factor activity, ligand-activated sequence-specific DNA binding
protein binding
phospholipid binding
zinc ion binding
sequence-specific DNA binding
sequence-specific double-stranded DNA binding
primary ovarian follicle growth
inner cell mass cell differentiation
positive regulation of T cell anergy
chromatin remodeling
regulation of transcription, DNA-templated
regulation of transcription from RNA polymerase II promoter
spermatogenesis
bile acid metabolic process
hormone-mediated signaling pathway
embryo development ending in birth or egg hatching
tissue development
neurogenesis
intracellular receptor signaling pathway
exocrine pancreas development
positive regulation of glucocorticoid biosynthetic process
negative regulation of chondrocyte differentiation
somatic stem cell population maintenance
embryonic cleavage
positive regulation of T cell proliferation
homeostatic process
positive regulation of viral genome replication
positive regulation of transcription, DNA-templated
positive regulation of transcription from RNA polymerase II promoter
negative regulation of inflammatory response
positive regulation of T cell activation
Sertoli cell development
calcineurin-mediated signaling
morula formation
zygotic genome activation
positive regulation of stem cell differentiation
positive regulation of tendon cell differentiation
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