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Invitrogen
MAPRE3 Monoclonal Antibody (KT53)
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MAPRE3 Antibody (MA5-47714) in WB
Western blot of MAPRE3 in mouse brain (lanes 1-5). The blot was probed with rat EB1 monoclonal antibody (Product # MA5-47663) (lane 1), EB1/EB2/EB3 monoclonal antibody (Product # MA5-47713) (lane 2), MAPRE2 monoclonal antibody (Product # MA5-47664) (lane 3), MAPRE3 monoclonal antibody (Product # MA5-47714) (lane 4), and anti-EB3 (lane 5). Then the antibodies were detected using goat anti-Rat IgG Light Chain specific: HRP.
产品信息
MA5-47714
产品规格
种属反应
Human,
Mouse,
Rat
宿主/亚型
Rat
/ IgG2a
分类
Monoclonal
类型
Antibody
克隆号
KT53
抗原
Clone KT53 was generated from a GST fusion protein containing human EB3. This sequence is highly conserved in rat and mouse EB3.
偶联物
形式
Liquid
浓度
~1 mg/mL
纯化类型
Protein G
保存液
PBS
内含物
0.05% sodium azide
保存条件
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
运输条件
Ambient (domestic); Wet ice (international)
RRID
产品详细信息
The antibody detects a 32 kDa* prtoein corresponding to the molecular mass of EB3 on SDS-PAGE immunoblots of human HeLa cells and mouse brain tissue. The antibody also detects EB3 by immunocytochemistry in HeLa and A431 cells.
靶标信息
EB3 is a 282 amino acid homologue of EB1, a protein known to bind APC (adenomatous polyposis coli). It has been shown to bind to tubulin in vitro and microtubules in vivo. Northern blotting shows expressions to be mainly in brain, and to a lesser degree in muscle. EB3 interacts with APCL, a homologue of the tumor suppressor APC, and this interaction may be involved in the stabilization or extension of microtubules.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
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生物信息学
蛋白别名: APC binding protein; EB1 protein family member 3; EB3; EBF3; End-binding protein 3; Microtubule-associated protein RP/EB family member 3; microtubule-associated protein, RP/EB family, member 3; RP3
基因别名: AI790651; EB2; EB3; EBF3; EBF3-S; MAPRE3; RP3
UniProt ID: (Human) Q9UPY8, (Mouse) Q6PER3, (Rat) Q5XIT1
Entrez Gene ID: (Human) 22924, (Mouse) 100732, (Rat) 298848
