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Invitrogen
GRP94 Monoclonal Antibody (25GB1625)
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图: 1 / 4
GRP94 Antibody (MA570383) in ICC/IF
Immunocytochemistry analysis of GRP94 in HAP-1 cells. Sample was incubated with GRP94 monoclonal antibody (Product # MA570383) at a dilution of 1:1,000. Nuclei were stained blue with DAPI and Alexa Fluor 647. Images were taken using Leica stellaris 5. Protein abundance based on laser Intensity and smart gain: Medium. Scale bar, 20 μm.
Please note: We are reviewing Western blot images included in the antibody testing data in our catalog, including those provided by third parties. Unless expressly labeled or annotated as “raw-unedited”, Western blot images included in the antibody testing data in our catalog may have been edited, optimized or otherwise adjusted for presentation.
产品信息
MA570383
产品规格
种属反应
Human
宿主/亚型
Mouse
/ IgG1
分类
Monoclonal
类型
Antibody
克隆号
25GB1625
抗原
Recombinant protein of human (51-610) HSP90B1.
偶联物
Unconjugated
Unconjugated
Unconjugated
形式
Liquid
纯化类型
Antigen affinity chromatography
保存液
PBS, pH 7.4, with 50% glycerol
内含物
0.02% sodium azide
保存条件
-20°C
运输条件
Ambient (domestic); Dry ice (international)
靶标信息
GRP94 is a 803 amino acid protein belonging to the heat shock protein 90 family. It acts as a molecular chaperone that functions in the processing and transport of secreted proteins. GRP94 and its N-terminal fragment stimulates CTL expansion and maturation of human monocyte-derived dendritic cells (MDDC). It plays a central role in innate as well as acquired immunity, maturation and chemotaxis of dendritic cells, Ab production, cross-priming, as a potential marker in breast cancer and is a peptide acceptor in endoplasmic reticulum and an accessory to peptide loading of MHC class I molecules. Expression of GRP94 suppressed A23187-induced apoptosis and stabilized calcium homeostasis. GRP94 is expressed in melanoma or liver metastases of colon carcinoma cells, human gastric carcinoma BGC-823 cells.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
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生物信息学
蛋白别名: 94 kDa glucose-regulated protein; Endoplasmin; gp96 homolog; GRP-94; Heat shock protein 90 kDa beta member 1; Heat shock protein family C member 4; Tumor rejection antigen 1
基因别名: GRP94; HSP90B1; HSPC4; TRA1
Entrez Gene ID: (Human) 7184
Disclaimer
Clicking the images or links will redirect you to a website hosted by BenchSci that provides third-party scientific content. Neither the content nor the BenchSci technology and processes for selection have been evaluated by us; we are providing them as-is and without warranty of any kind, including for use or application of the Thermo Fisher Scientific products presented.
