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Invitrogen
alpha E-Catenin/alpha N-Catenin Polyclonal Antibody
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Please note: We are reviewing Western blot images included in the antibody testing data in our catalog, including those provided by third parties. Unless expressly labeled or annotated as “raw-unedited”, Western blot images included in the antibody testing data in our catalog may have been edited, optimized or otherwise adjusted for presentation.
产品信息
PA5-99602
产品规格
种属反应
Human
宿主/亚型
Rabbit
/ IgG
分类
Polyclonal
类型
Antibody
抗原
A synthesized peptide derived from human CTNNA1/CTNNA2, corresponding to a region within C-terminal amino acids.
偶联物
Unconjugated
Unconjugated
Unconjugated
形式
Liquid
浓度
1 mg/mL
规格
100 µg
纯化类型
Affinity chromatography
保存液
PBS, pH 7.4, with 50% glycerol
内含物
0.02% sodium azide
保存条件
-20°C
运输条件
Ambient (domestic); Wet ice (international)
RRID
产品详细信息
Antibody detects endogenous levels of total CTNNA1/CTNNA2.
靶标信息
This gene encodes a member of the catenin family of proteins that play an important role in cell adhesion process by connecting cadherins located on the plasma membrane to the actin filaments inside the cell. The encoded mechanosensing protein contains three vinculin homology domains and undergoes conformational changes in response to cytoskeletal tension, resulting in the reconfiguration of cadherin-actin filament connections. Certain mutations in this gene cause butterfly-shaped pigment dystrophy.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
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生物信息学
蛋白别名: Alpha E-catenin; Alpha N-catenin; alpha-catenin; Alpha-catenin-related protein; alpha-E-catenin; alpha-N-catenin; Cadherin-associated protein; cadherin-associated protein, related; cancer/testis antigen 114; catenin (cadherin-associated protein), alpha 1, 102kDa; catenin (cadherin-associated protein), alpha 2; Catenin alpha-1; Catenin alpha-2; epididymis secretory sperm binding protein; Renal carcinoma antigen NY-REN-13; unnamed protein product
基因别名: CAP-R; CAP102; CAPR; CDCBM9; CT114; CTNNA1; CTNNA2; CTNR; MDBS2; MDPT2
Entrez Gene ID: (Human) 1495, (Human) 1496
ovarian follicle development
cell adhesion
male gonad development
gap junction assembly
cell migration
axon regeneration
odontogenesis of dentin-containing tooth
apical junction assembly
response to estrogen
cellular response to indole-3-methanol
cell-cell adhesion
negative regulation of protein localization to nucleus
cytoskeleton organization
axonogenesis
regulation of neuron projection development
radial glia guided migration of Purkinje cell
negative regulation of Arp2/3 complex-mediated actin nucleation
dendrite morphogenesis
brain morphogenesis
regulation of synapse structural plasticity
prepulse inhibition
modification of postsynaptic actin cytoskeleton
regulation of neuron migration
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Clicking the images or links will redirect you to a website hosted by BenchSci that provides third-party scientific content. Neither the content nor the BenchSci technology and processes for selection have been evaluated by us; we are providing them as-is and without warranty of any kind, including for use or application of the Thermo Fisher Scientific products presented.
