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          System Message

          OKCancel
          LOADING ...
          See other HIF1A SIRNA Assays ›
          Gene Symbol:
          HIF1A
          Gene Name:
          hypoxia inducible factor 1 alpha subunit
          Gene Aliases:
          HIF-1-alpha, HIF-1A, HIF-1alpha, HIF1, HIF1-ALPHA, MOP1, PASD8, bHLHe78
          Chromosome Location:
          Chr.14: 61695401 - 61748259 on Build GRCh38
          UniGene ID:
          Hs.597216
          Species:
          Human
          Species Specific ID (Flybase ID):
          -
          siRNA ID 106498

          Purification
          Size
          Availability Inventoried
          Catalog # AM16708
          Price
          Your Price
          Online offer:
          Check your price ›
          • Genomic Map
          • siRNA Details
          • More Information

          Genomic Map

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          siRNA Details

          Gene Symbol: HIF1A
          Interrogated Sequence Translated Protein Targeted Exon(s) siRNA Location IMAGE Clone ID
          RefSeq NM_001243084.1 NP_001230013.1 8 1216
          NM_001530.3 NP_001521.1 8 1319
          NM_181054.2 NP_851397.1 8 1319
          GenBank mRNA AB073325.1 - 8 943
          AB500182.1 - 8 940
          AF207601.1 - 8 925
          AF207602.1 - 8 922
          AF304431.1 - 8 915
          AK296876.1 - 8 1009
          AK299551.1 - 9 1021
          AK304315.1 - 8 1028
          AK304436.1 - 7 768
          AK312397.1 - 8 1148
          BC012527.2 - 8 1169 3842146
          BT009776.1 - 8 915
          BX648795.1 - 8 1183
          FJ790247.1 - 8 1217
          U22431.1 - 8 943
          U29165.1 - 8 1179

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          More Information


          Other Species Targeted

          This siRNA also targets the following transcripts in Rat: NM_024359, XM_006240197, XM_006240196, XM_006240199, XM_008764695, and others.
          This siRNA also targets the following transcripts in Mouse: NM_010431, BC026139, AK034087, AK138944, AK076395, and others.

          Panther Classification:

          Molecular Function -

          basic helix-loop-helix transcription factor

          Gene Ontology Categories:

          Function(s) Process(es)

          negative regulation of transcription from RNA polymerase II promoter
          angiogenesis
          response to hypoxia
          neural crest cell migration
          epithelial to mesenchymal transition
          embryonic placenta development
          B-1 B cell homeostasis
          positive regulation of endothelial cell proliferation
          heart looping
          positive regulation of neuroblast proliferation
          connective tissue replacement involved in inflammatory response wound healing
          outflow tract morphogenesis
          cardiac ventricle morphogenesis
          lactate metabolic process
          regulation of transcription, DNA-templated
          transcription from RNA polymerase II promoter
          cellular iron ion homeostasis
          acute-phase response
          signal transduction
          lactation
          visual learning
          response to salt stress
          response to X-ray
          regulation of gene expression
          vascular endothelial growth factor production
          positive regulation of vascular endothelial growth factor production
          positive regulation of gene expression
          positive regulation of epithelial cell migration
          positive regulation of receptor biosynthetic process
          response to auditory stimulus
          response to purine-containing compound
          response to muscle activity
          positive regulation of macroautophagy
          axonal transport of mitochondrion
          neural fold elevation formation
          cerebral cortex development
          negative regulation of bone mineralization
          positive regulation of vascular endothelial growth factor receptor signaling pathway
          negative regulation of TOR signaling
          response to estradiol
          oxygen homeostasis
          positive regulation of chemokine production
          cellular response to insulin stimulus
          regulation of transforming growth factor beta2 production
          collagen metabolic process
          embryonic hemopoiesis
          cellular response to drug
          positive regulation of insulin secretion involved in cellular response to glucose stimulus
          hemoglobin biosynthetic process
          mRNA transcription from RNA polymerase II promoter
          positive regulation of apoptotic process
          response to alkaloid
          regulation of transcription from RNA polymerase II promoter in response to oxidative stress
          response to estrogen
          positive regulation of erythrocyte differentiation
          positive regulation of angiogenesis
          positive regulation of cell size
          positive regulation of glycolytic process
          positive regulation of transcription, DNA-templated
          negative regulation of vasoconstriction
          negative regulation of growth
          positive regulation of transcription from RNA polymerase II promoter
          muscle cell cellular homeostasis
          positive regulation of hormone biosynthetic process
          digestive tract morphogenesis
          positive regulation of smooth muscle cell proliferation
          positive regulation of nitric-oxide synthase activity
          cartilage development
          response to glucocorticoid
          elastin metabolic process
          maternal process involved in female pregnancy
          intestinal epithelial cell maturation
          response to fungicide
          epithelial cell differentiation involved in mammary gland alveolus development
          iris morphogenesis
          retina vasculature development in camera-type eye
          regulation of transcription from RNA polymerase II promoter in response to hypoxia
          positive regulation of transcription from RNA polymerase II promoter in response to hypoxia
          positive regulation of chemokine-mediated signaling pathway
          negative regulation of thymocyte apoptotic process
          cellular response to hydrogen peroxide
          cellular response to lipopolysaccharide
          cellular response to carbon monoxide
          cellular response to nitrite
          cellular response to electrical stimulus
          cellular response to mechanical stimulus
          cellular response to cobalt ion
          cellular response to glucose stimulus
          cellular response to interleukin-1
          cellular response to organic cyclic compound
          cellular response to hypoxia
          cellular response to light stimulus
          dopaminergic neuron differentiation
          response to anesthetic
          cellular response to toxic substance
          hypoxia-inducible factor-1alpha signaling pathway
          regulation of cellular response to hypoxia
          positive regulation of pri-miRNA transcription from RNA polymerase II promoter
          negative regulation of oxidative stress-induced neuron intrinsic apoptotic signaling pathway
          positive regulation of mitophagy
          regulation of aerobic respiration
          cellular response to cyanide
          negative regulation of reactive oxygen species metabolic process
          negative regulation of mesenchymal cell apoptotic process
          transcription factor activity, transcription factor binding
          transcription factor activity, RNA polymerase II transcription factor binding
          transcriptional activator activity, RNA polymerase II core promoter proximal region sequence-specific binding
          transcriptional activator activity, RNA polymerase II transcription regulatory region sequence-specific binding
          transcription factor activity, sequence-specific DNA binding
          transcription factor activity, RNA polymerase II distal enhancer sequence-specific binding
          protein binding
          transcription factor binding
          enzyme binding
          protein kinase binding
          ubiquitin protein ligase binding
          protein complex binding
          histone acetyltransferase binding
          nuclear hormone receptor binding
          histone deacetylase binding
          sequence-specific DNA binding
          protein heterodimerization activity
          Hsp90 protein binding

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