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          System Message

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          LOADING ...
          See other SORL1 SIRNA Assays ›
          Gene Symbol:
          SORL1
          Gene Name:
          sortilin related receptor 1
          Gene Aliases:
          C11orf32, LR11, LRP9, SORLA, SorLA-1, gp250
          Chromosome Location:
          Chr.11: 121452203 - 121633762 on Build GRCh38
          UniGene ID:
          Hs.368592
          Species:
          Human
          Species Specific ID (Flybase ID):
          -
          siRNA ID 106968
          Validated

          Purification
          Size
          Availability Inventoried
          Catalog # AM51331
          Price
          Your Price
          Online offer:
          Check your price ›
          • Genomic Map
          • siRNA Details
          • More Information

          Genomic Map

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          siRNA Details

          Gene Symbol: SORL1
          Interrogated Sequence Translated Protein Targeted Exon(s) siRNA Location IMAGE Clone ID
          RefSeq NM_003105.5 NP_003096.1 9 1401
          XM_011542963.2 XP_011541265.1 9 1276
          XM_011542965.2 XP_011541267.1 2 227
          XM_017018169.1 XP_016873658.1 9 1108
          XM_017018170.1 XP_016873659.1 7 784
          XM_017018171.1 XP_016873660.1 9 1276
          GenBank mRNA AK309523.1 - 9 1224
          BC137171.1 - 9 1324 9021168
          Y08110.1 - 9 1352

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          More Information


          Matching Taqman Gene Expression Assay:


          Hs00268342_m1

          Panther Classification:

          Molecular Function -

          apolipoprotein membrane traffic protein

          Gene Ontology Categories:

          Function(s) Process(es)

          protein targeting to Golgi
          protein targeting
          protein targeting to lysosome
          lipid transport
          post-Golgi vesicle-mediated transport
          receptor-mediated endocytosis
          signal transduction
          cholesterol metabolic process
          regulation of smooth muscle cell migration
          negative regulation of protein binding
          negative regulation of protein oligomerization
          negative regulation of MAP kinase activity
          protein retention in Golgi apparatus
          positive regulation of protein catabolic process
          negative regulation of neurogenesis
          protein maturation
          positive regulation of protein exit from endoplasmic reticulum
          negative regulation of neuron death
          negative regulation of beta-amyloid formation
          positive regulation of choline O-acetyltransferase activity
          negative regulation of tau-protein kinase activity
          positive regulation of ER to Golgi vesicle-mediated transport
          positive regulation of early endosome to recycling endosome transport
          negative regulation of aspartic-type endopeptidase activity involved in amyloid precursor protein catabolic process
          negative regulation of metalloendopeptidase activity involved in amyloid precursor protein catabolic process
          positive regulation of protein localization to early endosome
          negative regulation of neurofibrillary tangle assembly
          positive regulation of endocytic recycling
          beta-amyloid binding
          transmembrane signaling receptor activity
          protein binding
          low-density lipoprotein particle binding
          ADP-ribosylation factor binding

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