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          System Message

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          LOADING ...
          See other PPARGC1A SIRNA Assays ›
          Gene Symbol:
          PPARGC1A
          Gene Name:
          PPARG coactivator 1 alpha
          Gene Aliases:
          LEM6, PGC-1(alpha), PGC-1alpha, PGC-1v, PGC1, PGC1A, PPARGC1
          Chromosome Location:
          Chr.4: 23792021 - 24472975 on Build GRCh38
          UniGene ID:
          Hs.527078
          Species:
          Human
          Species Specific ID (Flybase ID):
          -
          siRNA ID 108387

          Purification
          Size
          Availability Inventoried
          Catalog # AM16708
          Price 283.00
          Your Price
          Online offer: 274.65
          274.65
          Check your price ›
          • Genomic Map
          • siRNA Details
          • More Information

          Genomic Map

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          siRNA Details

          Gene Symbol: PPARGC1A
          Interrogated Sequence Translated Protein Targeted Exon(s) siRNA Location IMAGE Clone ID
          RefSeq NM_013261.3 NP_037393.1 13 3751
          XM_005248131.4 XP_005248188.1 13 4494
          XM_005248132.1 XP_005248189.1 13 3673
          XM_005248134.4 XP_005248191.1 11 3466
          XM_011513765.2 XP_011512067.1 14 4243
          XM_011513766.1 XP_011512068.1 14 3825
          XM_011513767.2 XP_011512069.1 14 5963
          XM_011513768.1 XP_011512070.1 13 3724
          XM_011513770.2 XP_011512072.1 12 3961
          XM_011513771.1 XP_011512073.1 12 3570
          XM_017007664.1 XP_016863153.1 15 4200
          GenBank mRNA AF106698.1 - 13 3739

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          More Information


          Other Species Targeted

          This siRNA also targets the following transcripts in Rat: XM_008770220, XM_008770219.
          This siRNA also targets the following transcripts in Mouse: NM_008904, AK082685, AK043827, AK032149.

          Panther Classification:

          Molecular Function -

          transcription cofactor

          Gene Ontology Categories:

          Function(s) Process(es)

          response to reactive oxygen species
          mitophagy
          temperature homeostasis
          cellular glucose homeostasis
          negative regulation of protein phosphorylation
          response to dietary excess
          response to ischemia
          galactose metabolic process
          gluconeogenesis
          regulation of transcription, DNA-templated
          transcription initiation from RNA polymerase II promoter
          mRNA processing
          protein complex assembly
          mitochondrion organization
          positive regulation of transcription from RNA polymerase II promoter by pheromones
          aging
          digestion
          circadian rhythm
          androgen metabolic process
          RNA splicing
          response to cold
          positive regulation of mitochondrion organization
          skeletal muscle atrophy
          response to muscle activity
          response to electrical stimulus involved in regulation of muscle adaptation
          negative regulation of smooth muscle cell migration
          fatty acid oxidation
          cerebellum development
          respiratory electron transport chain
          androgen receptor signaling pathway
          forebrain development
          circadian regulation of gene expression
          cellular response to oxidative stress
          positive regulation of histone acetylation
          cellular response to potassium ion
          response to statin
          response to drug
          response to starvation
          regulation of circadian rhythm
          response to leucine
          negative regulation of neuron apoptotic process
          cellular respiration
          positive regulation of gluconeogenesis
          negative regulation of glycolytic process
          positive regulation of transcription, DNA-templated
          positive regulation of transcription from RNA polymerase II promoter
          positive regulation of fatty acid oxidation
          positive regulation of smooth muscle cell proliferation
          negative regulation of smooth muscle cell proliferation
          protein stabilization
          brown fat cell differentiation
          positive regulation of sequence-specific DNA binding transcription factor activity
          flavone metabolic process
          adipose tissue development
          cellular response to lipopolysaccharide
          cellular response to nitrite
          cellular response to caffeine
          cellular response to fructose stimulus
          cellular response to glucose stimulus
          cellular response to interleukin-6
          cellular response to tumor necrosis factor
          cellular response to follicle-stimulating hormone stimulus
          cellular response to estradiol stimulus
          cellular response to hypoxia
          cellular response to transforming growth factor beta stimulus
          response to epinephrine
          response to norepinephrine
          negative regulation of mitochondrial fission
          cellular response to thyroid hormone stimulus
          negative regulation of neuron death
          response to metformin
          positive regulation of cellular respiration
          positive regulation of mitochondrial DNA metabolic process
          positive regulation of muscle tissue development
          positive regulation of glomerular visceral epithelial cell apoptotic process
          cellular response to ionomycin
          cellular response to resveratrol
          response to methionine
          adaptive thermogenesis
          positive regulation of progesterone biosynthetic process
          negative regulation of receptor activity
          regulation of N-methyl-D-aspartate selective glutamate receptor activity
          positive regulation of energy homeostasis
          positive regulation of ATP biosynthetic process
          nucleotide binding
          RNA polymerase II transcription cofactor activity
          DNA binding
          transcription coactivator activity
          RNA binding
          protein binding
          transcription factor binding
          ligand-dependent nuclear receptor binding
          estrogen receptor binding
          ligand-dependent nuclear receptor transcription coactivator activity
          chromatin DNA binding
          ubiquitin protein ligase binding
          peroxisome proliferator activated receptor binding
          alpha-tubulin binding
          sequence-specific DNA binding
          androgen receptor binding
          promoter-specific chromatin binding

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