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          System Message

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          LOADING ...
          See other PINK1 SIRNA Assays ›
          Gene Symbol:
          PINK1
          Gene Name:
          PTEN induced putative kinase 1
          Gene Aliases:
          BRPK, PARK6
          Chromosome Location:
          Chr.1: 20633455 - 20651511 on Build GRCh38
          UniGene ID:
          Hs.389171
          Species:
          Human
          Species Specific ID (Flybase ID):
          -
          siRNA ID 131313

          Purification
          Size
          Availability Inventoried
          Catalog # AM16708
          Price
          Your Price
          Online offer:
          Check your price ›
          • Genomic Map
          • siRNA Details
          • More Information

          Genomic Map

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          siRNA Details

          Gene Symbol: PINK1
          Interrogated Sequence Translated Protein Targeted Exon(s) siRNA Location IMAGE Clone ID
          RefSeq NM_032409.2 NP_115785.1 8 2328
          GenBank mRNA AB053323.1 - 8 2328
          AF316873.1 - 8 2304
          AK075225.1 - 4 1327
          AK130746.1 - 5 2793
          BC009534.1 - 5 1401
          BC028215.1 - 8 2243 5214483

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          More Information


          Panther Classification:

          Molecular Function -

          non-receptor serine/threonine protein kinase protein modifying enzyme

          Gene Ontology Categories:

          Function(s) Process(es)

          mitophagy
          positive regulation of protein phosphorylation
          regulation of oxidative phosphorylation
          protein phosphorylation
          ubiquitin-dependent protein catabolic process
          response to stress
          response to oxidative stress
          mitochondrion organization
          regulation of hydrogen peroxide metabolic process
          negative regulation of gene expression
          regulation of mitochondrion organization
          positive regulation of peptidase activity
          macroautophagy
          positive regulation of macroautophagy
          negative regulation of macroautophagy
          phosphorylation
          protein ubiquitination
          peptidyl-serine phosphorylation
          respiratory electron transport chain
          regulation of protein ubiquitination
          positive regulation of protein ubiquitination
          activation of protein kinase B activity
          positive regulation of synaptic transmission, dopaminergic
          positive regulation of peptidyl-serine phosphorylation
          positive regulation of dopamine secretion
          cellular response to oxidative stress
          positive regulation of protein dephosphorylation
          intracellular signal transduction
          peptidyl-serine autophosphorylation
          TORC2 signaling
          positive regulation of I-kappaB kinase/NF-kappaB signaling
          regulation of protein complex assembly
          negative regulation of neuron apoptotic process
          positive regulation of translation
          negative regulation of JNK cascade
          protein stabilization
          positive regulation of sequence-specific DNA binding transcription factor activity
          positive regulation of ubiquitin-protein transferase activity
          regulation of mitochondrial membrane potential
          positive regulation of protein kinase B signaling
          regulation of proteasomal protein catabolic process
          cellular response to hypoxia
          establishment of protein localization to mitochondrion
          maintenance of protein location in mitochondrion
          positive regulation of mitochondrial fission
          positive regulation of release of cytochrome c from mitochondria
          negative regulation of mitochondrial fission
          cellular response to toxic substance
          mitophagy in response to mitochondrial depolarization
          regulation of synaptic vesicle transport
          negative regulation of autophagosome assembly
          positive regulation of mitochondrial electron transport, NADH to ubiquinone
          regulation of mitophagy
          negative regulation of mitophagy
          negative regulation of oxidative stress-induced cell death
          negative regulation of oxidative stress-induced neuron death
          regulation of protein targeting to mitochondrion
          negative regulation of hypoxia-induced intrinsic apoptotic signaling pathway
          negative regulation of hydrogen peroxide-induced neuron intrinsic apoptotic signaling pathway
          negative regulation of intrinsic apoptotic signaling pathway in response to hydrogen peroxide
          positive regulation of cristae formation
          positive regulation of protein targeting to mitochondrion
          positive regulation of free ubiquitin chain polymerization
          regulation of reactive oxygen species metabolic process
          negative regulation of reactive oxygen species metabolic process
          positive regulation of ATP biosynthetic process
          magnesium ion binding
          protease binding
          protein kinase activity
          protein serine/threonine kinase activity
          protein binding
          ATP binding
          calcium-dependent protein kinase activity
          kinase activity
          peptidase activator activity
          ubiquitin protein ligase binding
          protein kinase B binding
          C3HC4-type RING finger domain binding

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