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          System Message

          OKCancel
          LOADING ...
          See other NOTCH1 SIRNA Assays ›
          Gene Symbol:
          NOTCH1
          Gene Name:
          notch 1
          Gene Aliases:
          AOS5, AOVD1, TAN1, hN1
          Chromosome Location:
          Chr.9: 136494433 - 136545786 on Build GRCh38
          UniGene ID:
          Hs.495473
          Species:
          Human
          Species Specific ID (Flybase ID):
          -
          siRNA ID 144335

          Purification
          Size
          Availability Inventoried
          Catalog # AM16708
          Price
          Your Price
          Online offer:
          Check your price ›
          • Genomic Map
          • siRNA Details
          • More Information

          Genomic Map

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          siRNA Details

          Gene Symbol: NOTCH1
          Interrogated Sequence Translated Protein Targeted Exon(s) siRNA Location IMAGE Clone ID
          RefSeq NM_017617.4 NP_060087.3 34 8284
          XM_011518717.2 XP_011517019.2 31 7576
          GenBank mRNA AB209873.1 - 26 6821
          AK000012.1 - 1 460
          BC013208.1 - 4 2469
          BC046127.1 - 1 35

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          More Information


          Panther Classification:

          Molecular Function -

          cell adhesion molecule

          Gene Ontology Categories:

          Function(s) Process(es)

          negative regulation of transcription from RNA polymerase II promoter
          in utero embryonic development
          cell fate specification
          epithelial to mesenchymal transition
          liver development
          heart looping
          sprouting angiogenesis
          positive regulation of neuroblast proliferation
          inflammatory response to antigenic stimulus
          endocardium development
          endocardium morphogenesis
          atrioventricular node development
          coronary vein morphogenesis
          aortic valve morphogenesis
          atrioventricular valve morphogenesis
          pulmonary valve morphogenesis
          mitral valve formation
          epithelial to mesenchymal transition involved in endocardial cushion formation
          endocardial cushion morphogenesis
          cardiac chamber formation
          cardiac ventricle morphogenesis
          cardiac atrium morphogenesis
          cardiac right atrium morphogenesis
          cardiac left ventricle morphogenesis
          cardiac right ventricle formation
          ventricular trabecula myocardium morphogenesis
          growth involved in heart morphogenesis
          regulation of transcription from RNA polymerase II promoter involved in myocardial precursor cell differentiation
          Notch signaling pathway involved in regulation of secondary heart field cardioblast proliferation
          cell migration involved in endocardial cushion formation
          pericardium morphogenesis
          regulation of transcription, DNA-templated
          transcription initiation from RNA polymerase II promoter
          immune response
          humoral immune response
          Notch signaling pathway
          positive regulation of transcription of Notch receptor target
          spermatogenesis
          determination of left/right symmetry
          compartment pattern specification
          axonogenesis
          foregut morphogenesis
          endoderm development
          heart development
          positive regulation of cell proliferation
          negative regulation of cell proliferation
          auditory receptor cell fate commitment
          positive regulation of epithelial to mesenchymal transition
          negative regulation of cell-substrate adhesion
          negative regulation of myotube differentiation
          mesenchymal cell development
          regulation of somitogenesis
          cell differentiation in spinal cord
          neural tube development
          keratinocyte differentiation
          negative regulation of ossification
          lung development
          positive regulation of cell migration
          positive regulation of BMP signaling pathway
          negative regulation of BMP signaling pathway
          forebrain development
          hair follicle morphogenesis
          organ regeneration
          response to corticosteroid
          response to muramyl dipeptide
          response to lipopolysaccharide
          embryonic hindlimb morphogenesis
          tube formation
          skeletal muscle cell differentiation
          cellular response to vascular endothelial growth factor stimulus
          tissue regeneration
          positive regulation of apoptotic process
          negative regulation of catalytic activity
          positive regulation of viral genome replication
          positive regulation of endothelial cell differentiation
          negative regulation of auditory receptor cell differentiation
          positive regulation of keratinocyte differentiation
          negative regulation of myoblast differentiation
          negative regulation of osteoblast differentiation
          positive regulation of Notch signaling pathway
          negative regulation of transcription, DNA-templated
          positive regulation of transcription, DNA-templated
          positive regulation of transcription from RNA polymerase II promoter
          negative regulation of calcium ion-dependent exocytosis
          positive regulation of JAK-STAT cascade
          negative regulation of photoreceptor cell differentiation
          somatic stem cell division
          astrocyte differentiation
          oligodendrocyte differentiation
          positive regulation of astrocyte differentiation
          negative regulation of oligodendrocyte differentiation
          branching morphogenesis of an epithelial tube
          positive regulation of viral transcription
          positive regulation of epithelial cell proliferation
          negative regulation of neurogenesis
          cardiac muscle tissue morphogenesis
          cardiac muscle cell proliferation
          positive regulation of cardiac muscle cell proliferation
          negative regulation of glial cell proliferation
          cilium morphogenesis
          cardiac epithelial to mesenchymal transition
          cardiac septum morphogenesis
          ventricular septum morphogenesis
          secretory columnal luminar epithelial cell differentiation involved in prostate glandular acinus development
          prostate gland epithelium morphogenesis
          regulation of epithelial cell proliferation involved in prostate gland development
          arterial endothelial cell differentiation
          venous endothelial cell differentiation
          cardiac vascular smooth muscle cell development
          endocardial cell differentiation
          vasculogenesis involved in coronary vascular morphogenesis
          coronary artery morphogenesis
          Notch signaling involved in heart development
          heart trabecula morphogenesis
          positive regulation of transcription from RNA polymerase II promoter in response to hypoxia
          left/right axis specification
          cellular response to follicle-stimulating hormone stimulus
          distal tubule development
          collecting duct development
          glomerular mesangial cell development
          interleukin-4 secretion
          negative regulation of cell migration involved in sprouting angiogenesis
          negative regulation of canonical Wnt signaling pathway
          neuronal stem cell population maintenance
          regulation of extracellular matrix assembly
          apoptotic process involved in embryonic digit morphogenesis
          negative regulation of stem cell differentiation
          negative regulation of anoikis
          negative regulation of pro-B cell differentiation
          negative regulation of endothelial cell chemotaxis
          core promoter binding
          transcriptional activator activity, RNA polymerase II transcription factor binding
          transcription factor activity, sequence-specific DNA binding
          enzyme inhibitor activity
          receptor activity
          Notch binding
          calcium ion binding
          protein binding
          enzyme binding
          chromatin DNA binding
          sequence-specific DNA binding
          protein heterodimerization activity

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