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          System Message

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          LOADING ...
          See other CD74 SIRNA Assays ›
          Gene Symbol:
          Cd74
          Gene Name:
          CD74 antigen (invariant polypeptide of major histocompatibility complex, class II antigen-associated)
          Gene Aliases:
          CLIP, DHLAG, HLADG, Ia-GAMMA, Ii
          Chromosome Location:
          Chr.18: 60803849 - 60812652 on Build GRCm38
          UniGene ID:
          Mm.439737
          Species:
          Mouse
          Species Specific ID (Flybase ID):
          -
          siRNA ID 159137

          Purification
          Size
          Availability Inventoried
          Catalog # AM16708
          Price
          Your Price
          Online offer:
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          • Genomic Map
          • siRNA Details
          • More Information

          Genomic Map

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          siRNA Details

          Gene Symbol: Cd74
          Interrogated Sequence Translated Protein Targeted Exon(s) siRNA Location IMAGE Clone ID
          RefSeq NM_001042605.1 NP_001036070.1 2 239
          NM_010545.3 NP_034675.1 2 239
          GenBank mRNA AK002232.1 - 2 239
          AK020607.1 - 2 240
          AK154096.1 - 2 270
          BC003476.1 - 2 239 2650401
          BC096435.1 - 2 250 6530802
          X00496.1 - 1 16
          X07129.1 - 2 232

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          More Information


          Other Species Targeted

          This siRNA also targets the following transcripts in Rat: NM_013069, XM_006254761, FQ233706, CB696567, FQ228116, and others.

          Panther Classification:

          Molecular Function -

          scaffold/adaptor protein

          Gene Ontology Categories:

          Function(s) Process(es)

          activation of MAPK activity
          prostaglandin biosynthetic process
          positive regulation of cytokine-mediated signaling pathway
          immune system process
          positive regulation of dendritic cell antigen processing and presentation
          negative regulation of peptide secretion
          positive regulation of adaptive immune response
          positive regulation of type 2 immune response
          negative regulation of mature B cell apoptotic process
          protein folding
          protein complex assembly
          intracellular protein transport
          defense response
          immune response
          signal transduction
          cell proliferation
          immunoglobulin mediated immune response
          cytokine-mediated signaling pathway
          antigen processing and presentation
          antigen processing and presentation of exogenous peptide antigen via MHC class II
          positive regulation of B cell proliferation
          macrophage migration inhibitory factor signaling pathway
          negative regulation of apoptotic process
          negative regulation of DNA damage response, signal transduction by p53 class mediator
          positive thymic T cell selection
          negative thymic T cell selection
          positive regulation of innate immune response
          negative regulation of T cell differentiation
          positive regulation of T cell differentiation
          positive regulation of fibroblast proliferation
          positive regulation of peptidyl-tyrosine phosphorylation
          chaperone mediated protein folding requiring cofactor
          positive regulation of macrophage cytokine production
          positive regulation of ERK1 and ERK2 cascade
          positive regulation of neutrophil chemotaxis
          negative regulation of intrinsic apoptotic signaling pathway in response to DNA damage by p53 class mediator
          positive regulation of chemokine (C-X-C motif) ligand 2 production
          beta-amyloid binding
          cytokine receptor activity
          protein binding
          cytokine binding
          MHC class II protein complex binding
          macrophage migration inhibitory factor binding
          MHC class II protein binding
          MHC class II protein binding, via antigen binding groove
          protein binding involved in protein folding
          nitric-oxide synthase binding

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