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          System Message

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          LOADING ...
          See other SIRT2 SIRNA Assays ›
          Gene Symbol:
          Sirt2
          Gene Name:
          sirtuin 2
          Gene Aliases:
          -
          Chromosome Location:
          Chr.1: 86948881 - 86971954 on Build Rnor_6.0
          UniGene ID:
          Rn.59887
          Species:
          Rat
          Species Specific ID (Flybase ID):
          -
          siRNA ID 223874

          Purification
          Size
          Availability Inventoried
          Catalog # AM16708
          Price
          Your Price
          Online offer:
          Check your price ›
          • Genomic Map
          • siRNA Details
          • More Information

          Genomic Map

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          siRNA Details

          Gene Symbol: Sirt2
          Interrogated Sequence Translated Protein Targeted Exon(s) siRNA Location IMAGE Clone ID
          RefSeq NM_001008368.1 NP_001008369.1 13 1276
          XM_006228672.2 XP_006228734.1 12 1224
          XM_006228673.2 XP_006228735.1 13 1229
          XM_006228675.1 XP_006228737.1 13 1008
          XM_006228676.2 XP_006228738.1 14 1013
          GenBank mRNA BC086545.1 - 13 1276 7134377
          FQ212805.1 - 13 935

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          More Information


          Gene Ontology Categories:

          Function(s) Process(es)

          negative regulation of transcription from RNA polymerase II promoter
          transcription, DNA-templated
          protein deacetylation
          autophagy
          mitotic nuclear division
          central nervous system development
          negative regulation of cell proliferation
          negative regulation of autophagy
          negative regulation of peptidyl-threonine phosphorylation
          phosphatidylinositol 3-kinase signaling
          histone deacetylation
          substantia nigra development
          myelination in peripheral nervous system
          regulation of myelination
          positive regulation of proteasomal ubiquitin-dependent protein catabolic process
          cellular response to oxidative stress
          peptidyl-lysine deacetylation
          cellular response to hepatocyte growth factor stimulus
          negative regulation of protein catabolic process
          negative regulation of apoptotic process
          proteasome-mediated ubiquitin-dependent protein catabolic process
          positive regulation of DNA binding
          protein kinase B signaling
          cellular lipid catabolic process
          regulation of fat cell differentiation
          negative regulation of fat cell differentiation
          positive regulation of meiotic nuclear division
          negative regulation of striated muscle tissue development
          negative regulation of transcription, DNA-templated
          positive regulation of transcription from RNA polymerase II promoter
          hepatocyte growth factor receptor signaling pathway
          negative regulation of oligodendrocyte differentiation
          cell division
          meiotic cell cycle
          regulation of cell cycle
          positive regulation of cell division
          positive regulation of attachment of spindle microtubules to kinetochore
          negative regulation of transcription from RNA polymerase II promoter in response to hypoxia
          cellular response to caloric restriction
          negative regulation of oligodendrocyte progenitor proliferation
          histone H3 deacetylation
          histone H4 deacetylation
          cellular response to molecule of bacterial origin
          cellular response to hypoxia
          cellular response to epinephrine stimulus
          tubulin deacetylation
          positive regulation of execution phase of apoptosis
          positive regulation of oocyte maturation
          negative regulation of NLRP3 inflammasome complex assembly
          negative regulation of defense response to bacterium
          ripoptosome assembly involved in necroptotic process
          negative regulation of reactive oxygen species metabolic process
          positive regulation of proteasomal ubiquitin-dependent protein catabolic process involved in cellular response to hypoxia
          molecular_function
          chromatin binding
          histone deacetylase activity
          transcription factor binding
          zinc ion binding
          NAD-dependent histone deacetylase activity
          protein deacetylase activity
          NAD-dependent protein deacetylase activity
          histone acetyltransferase binding
          histone deacetylase binding
          tubulin deacetylase activity
          ubiquitin binding
          NAD-dependent histone deacetylase activity (H4-K16 specific)
          beta-tubulin binding
          NAD+ binding

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