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          System Message

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          LOADING ...
          See other TP53 SIRNA Assays ›
          Gene Symbol:
          Tp53
          Gene Name:
          tumor protein p53
          Gene Aliases:
          Trp53, p53
          Chromosome Location:
          Chr.10: 56187013 - 56198449 on Build Rnor_6.0
          UniGene ID:
          Rn.54443
          Species:
          Rat
          Species Specific ID (Flybase ID):
          -
          siRNA ID 53153

          Purification
          Size
          Availability Inventoried
          Catalog # AM16708
          Price 283.00
          Your Price
          Online offer: 274.65
          274.65
          Check your price ›
          • Genomic Map
          • siRNA Details
          • More Information

          Genomic Map

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          siRNA Details

          Gene Symbol: Tp53
          Interrogated Sequence Translated Protein Targeted Exon(s) siRNA Location IMAGE Clone ID
          RefSeq NM_030989.3 NP_112251.2 4 446
          XM_006246594.2 XP_006246656.1 5 875
          XM_006246595.2 XP_006246657.1 4 1232
          XM_008767773.1 XP_008765995.1 4 453
          GenBank mRNA AF209191.1 - 3 338
          BC081788.1 - 4 375 7193583
          BC098663.1 - 4 404 7384467
          CV126174.1 - 4 446
          FQ232659.1 - 4 430
          X13058.1 - 3 338

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          More Information


          Panther Classification:

          Molecular Function -

          P53-like transcription factor

          Gene Ontology Categories:

          Function(s) Process(es)

          protein import into nucleus, translocation
          negative regulation of transcription from RNA polymerase II promoter
          DNA strand renaturation
          in utero embryonic development
          somitogenesis
          release of cytochrome c from mitochondria
          T cell proliferation involved in immune response
          B cell lineage commitment
          T cell lineage commitment
          positive regulation of leukocyte migration
          response to ischemia
          nucleotide-excision repair
          double-strand break repair
          regulation of transcription, DNA-templated
          regulation of transcription from RNA polymerase II promoter
          transcription from RNA polymerase II promoter
          protein complex assembly
          apoptotic process
          cellular response to DNA damage stimulus
          DNA damage response, signal transduction by p53 class mediator resulting in cell cycle arrest
          DNA damage response, signal transduction by p53 class mediator resulting in transcription of p21 class mediator
          response to oxidative stress
          ER overload response
          cell cycle arrest
          transforming growth factor beta receptor signaling pathway
          Ras protein signal transduction
          multicellular organism development
          gastrulation
          negative regulation of neuroblast proliferation
          central nervous system development
          aging
          cell aging
          protein localization
          negative regulation of DNA replication
          negative regulation of cell proliferation
          determination of adult lifespan
          rRNA transcription
          response to UV
          response to salt stress
          embryo development ending in birth or egg hatching
          response to inorganic substance
          response to metal ion
          response to X-ray
          response to UV-B
          response to organonitrogen compound
          response to gamma radiation
          positive regulation of cardiac muscle cell apoptotic process
          response to organic cyclic compound
          cerebellum development
          negative regulation of cell growth
          DNA damage response, signal transduction by p53 class mediator
          negative regulation of transforming growth factor beta receptor signaling pathway
          response to caffeine
          positive regulation of histone deacetylation
          chromatin assembly
          mitotic G1 DNA damage checkpoint
          positive regulation of protein oligomerization
          response to retinoic acid
          T cell differentiation in thymus
          response to vitamin B3
          response to cytokine
          regulation of tissue remodeling
          cellular response to heat
          cellular protein localization
          cellular response to UV
          multicellular organism growth
          cellular response to drug
          positive regulation of mitochondrial membrane permeability
          wound healing
          regulation of cell proliferation
          cellular response to glucose starvation
          response to drug
          intrinsic apoptotic signaling pathway in response to DNA damage by p53 class mediator
          regulation of apoptotic process
          positive regulation of apoptotic process
          negative regulation of apoptotic process
          entrainment of circadian clock by photoperiod
          response to amino acid
          mitochondrial DNA repair
          regulation of neuron apoptotic process
          positive regulation of neuron apoptotic process
          positive regulation of cell cycle
          negative regulation of proteolysis
          negative regulation of transcription, DNA-templated
          positive regulation of transcription, DNA-templated
          negative regulation of mitotic cell cycle
          positive regulation of transcription from RNA polymerase II promoter
          response to antibiotic
          negative regulation of fibroblast proliferation
          circadian behavior
          embryonic organ development
          negative regulation of smooth muscle cell proliferation
          positive regulation of peptidyl-tyrosine phosphorylation
          regulation of catalytic activity
          protein tetramerization
          chromosome organization
          neuron apoptotic process
          regulation of intracellular pH
          regulation of cell cycle
          response to hyperoxia
          regulation of thymocyte apoptotic process
          positive regulation of thymocyte apoptotic process
          necroptotic process
          positive regulation of cell cycle arrest
          cellular response to organonitrogen compound
          cellular response to hypoxia
          cellular response to ionizing radiation
          mitotic cell cycle arrest
          intrinsic apoptotic signaling pathway by p53 class mediator
          positive regulation of release of cytochrome c from mitochondria
          positive regulation of cell aging
          replicative senescence
          oxidative stress-induced premature senescence
          oligodendrocyte apoptotic process
          negative regulation of macromitophagy
          regulation of mitochondrial membrane permeability involved in apoptotic process
          regulation of intrinsic apoptotic signaling pathway by p53 class mediator
          regulation of hydrogen peroxide-induced cell death
          regulation of fibroblast apoptotic process
          negative regulation of DNA biosynthetic process
          negative regulation of reactive oxygen species metabolic process
          positive regulation of reactive oxygen species metabolic process
          regulation of cellular senescence
          positive regulation of intrinsic apoptotic signaling pathway
          RNA polymerase II regulatory region sequence-specific DNA binding
          RNA polymerase II core promoter sequence-specific DNA binding
          RNA polymerase II transcription factor activity, sequence-specific DNA binding
          core promoter sequence-specific DNA binding
          transcriptional activator activity, RNA polymerase II core promoter proximal region sequence-specific binding
          RNA polymerase II transcription factor binding
          transcription cofactor binding
          transcriptional activator activity, RNA polymerase II transcription regulatory region sequence-specific binding
          protease binding
          p53 binding
          DNA binding
          chromatin binding
          damaged DNA binding
          double-stranded DNA binding
          transcription factor activity, sequence-specific DNA binding
          copper ion binding
          protein binding
          ATP binding
          protein C-terminus binding
          transcription factor binding
          enzyme binding
          protein kinase binding
          protein phosphatase binding
          receptor tyrosine kinase binding
          ubiquitin protein ligase binding
          histone deacetylase regulator activity
          histone acetyltransferase binding
          identical protein binding
          sequence-specific DNA binding
          transcription regulatory region DNA binding
          protein heterodimerization activity
          protein N-terminus binding
          chaperone binding
          protein phosphatase 2A binding
          MDM2/MDM4 family protein binding

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