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          System Message

          OKCancel
          LOADING ...
          See other ACVR1 SIRNA Assays ›
          Gene Symbol:
          ACVR1
          Gene Name:
          activin A receptor type 1
          Gene Aliases:
          ACTRI, ACVR1A, ACVRLK2, ALK2, FOP, SKR1, TSRI
          Chromosome Location:
          Chr.2: 157736446 - 157875880 on Build GRCh38
          UniGene ID:
          Hs.470316
          Species:
          Human
          Species Specific ID (Flybase ID):
          -
          siRNA ID 76

          Purification
          Size
          Availability Inventoried
          Catalog # AM51331
          Price
          Your Price
          Online offer:
          Check your price ›
          • Genomic Map
          • siRNA Details
          • More Information

          Genomic Map

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          siRNA Details

          Gene Symbol: ACVR1
          Interrogated Sequence Translated Protein Targeted Exon(s) siRNA Location IMAGE Clone ID
          RefSeq NM_001105.4 NP_001096.1 4 643
          NM_001111067.2 NP_001104537.1 4 462
          XM_005246939.3 XP_005246996.1 4 514
          XM_005246940.3 XP_005246997.1 4 482
          XM_006712825.3 XP_006712888.1 4 595
          XM_011512106.2 XP_011510408.1 5 562
          XM_011512107.2 XP_011510409.1 4 534
          XM_011512108.2 XP_011510410.1 4 1941
          GenBank mRNA AK297765.1 - 4 430
          BC033867.1 - 4 643 5209711
          BC036748.1 - 4 643
          DA796090.1 - 4 462
          KU177885.1 - 2 213
          KU177886.1 - 2 213
          KU177887.1 - 2 213
          L02911.1 - 5 553
          Z22534.1 - 3 316

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          More Information


          Panther Classification:

          Molecular Function -

          serine/threonine protein kinase receptor

          Gene Ontology Categories:

          Function(s) Process(es)

          G1/S transition of mitotic cell cycle
          patterning of blood vessels
          in utero embryonic development
          gastrulation with mouth forming second
          mesoderm formation
          neural crest cell migration
          acute inflammatory response
          embryonic heart tube morphogenesis
          outflow tract septum morphogenesis
          atrioventricular valve morphogenesis
          mitral valve morphogenesis
          endocardial cushion morphogenesis
          endocardial cushion fusion
          atrial septum primum morphogenesis
          protein phosphorylation
          transforming growth factor beta receptor signaling pathway
          germ cell development
          determination of left/right symmetry
          negative regulation of signal transduction
          positive regulation of pathway-restricted SMAD protein phosphorylation
          peptidyl-threonine phosphorylation
          signal transduction by protein phosphorylation
          regulation of ossification
          positive regulation of cell migration
          positive regulation of bone mineralization
          BMP signaling pathway
          activin receptor signaling pathway
          negative regulation of activin receptor signaling pathway
          positive regulation of osteoblast differentiation
          positive regulation of transcription, DNA-templated
          positive regulation of transcription from RNA polymerase II promoter
          smooth muscle cell differentiation
          pharyngeal system development
          pathway-restricted SMAD protein phosphorylation
          ventricular septum morphogenesis
          cardiac muscle cell fate commitment
          BMP signaling pathway involved in heart development
          endocardial cushion cell fate commitment
          cellular response to glucocorticoid stimulus
          cellular response to BMP stimulus
          positive regulation of epithelial to mesenchymal transition involved in endocardial cushion formation
          positive regulation of determination of dorsal identity
          negative regulation of extrinsic apoptotic signaling pathway
          protein kinase activity
          protein serine/threonine kinase activity
          transmembrane receptor protein serine/threonine kinase activity
          receptor signaling protein serine/threonine kinase activity
          transforming growth factor beta receptor activity, type I
          protein binding
          ATP binding
          activin receptor activity, type I
          peptide hormone binding
          protein homodimerization activity
          SMAD binding
          metal ion binding
          activin binding
          transforming growth factor beta binding

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