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          System Message

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          LOADING ...
          See other PML SIRNA Assays ›
          Gene Symbol:
          Pml
          Gene Name:
          promyelocytic leukemia
          Gene Aliases:
          1200009E24Rik, AI661194, Trim19
          Chromosome Location:
          Chr.9: 58217179 - 58249796 on Build GRCm38
          UniGene ID:
          Mm.392123
          Species:
          Mouse
          Species Specific ID (Flybase ID):
          -
          siRNA ID 99659

          Purification
          Size
          Availability Inventoried
          Catalog # AM16708
          Price
          Your Price
          Online offer:
          Check your price ›
          • Genomic Map
          • siRNA Details
          • More Information

          Genomic Map

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          siRNA Details

          Gene Symbol: Pml
          Interrogated Sequence Translated Protein Targeted Exon(s) siRNA Location IMAGE Clone ID
          RefSeq NM_008884.5 NP_032910.3 8 3276
          NM_178087.4 NP_835188.2 9 3414
          GenBank mRNA AK028044.1 - 9 3416
          AK032799.1 - 7 2294
          AK137538.1 - 9 3357
          AK156279.1 - 9 3569
          BC020990.1 - 9 3221 4188386
          U33626.2 - 8 3173

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          More Information


          Gene Ontology Categories:

          Function(s) Process(es)

          response to hypoxia
          regulation of protein phosphorylation
          positive regulation of defense response to virus by host
          immune system process
          transcription, DNA-templated
          regulation of transcription, DNA-templated
          protein complex assembly
          protein targeting
          apoptotic process
          activation of cysteine-type endopeptidase activity involved in apoptotic process
          DNA damage response, signal transduction by p53 class mediator resulting in cell cycle arrest
          cell cycle arrest
          transforming growth factor beta receptor signaling pathway
          common-partner SMAD protein phosphorylation
          SMAD protein import into nucleus
          cell aging
          negative regulation of cell proliferation
          intrinsic apoptotic signaling pathway in response to DNA damage
          intrinsic apoptotic signaling pathway in response to oxidative stress
          response to UV
          response to gamma radiation
          regulation of calcium ion transport into cytosol
          viral process
          negative regulation of angiogenesis
          myeloid cell differentiation
          negative regulation of cell growth
          PML body organization
          positive regulation of histone deacetylation
          negative regulation of telomere maintenance via telomerase
          endoplasmic reticulum calcium ion homeostasis
          circadian regulation of gene expression
          negative regulation of translation in response to oxidative stress
          response to cytokine
          regulation of circadian rhythm
          intrinsic apoptotic signaling pathway in response to DNA damage by p53 class mediator
          entrainment of circadian clock by photoperiod
          proteasome-mediated ubiquitin-dependent protein catabolic process
          innate immune response
          cell fate commitment
          regulation of MHC class I biosynthetic process
          negative regulation of transcription, DNA-templated
          negative regulation of mitotic cell cycle
          retinoic acid receptor signaling pathway
          rhythmic process
          negative regulation of interleukin-1 secretion
          negative regulation of interleukin-1 beta secretion
          protein stabilization
          maintenance of protein location in nucleus
          defense response to virus
          negative regulation of telomerase activity
          positive regulation of apoptotic process involved in mammary gland involution
          branching involved in mammary gland duct morphogenesis
          intrinsic apoptotic signaling pathway in response to endoplasmic reticulum stress
          cellular response to interleukin-4
          intrinsic apoptotic signaling pathway by p53 class mediator
          cellular senescence
          extrinsic apoptotic signaling pathway
          negative regulation of viral release from host cell
          regulation of nucleic acid-templated transcription
          negative regulation of protein ubiquitination involved in ubiquitin-dependent protein catabolic process
          regulation of double-strand break repair
          positive regulation of apoptotic signaling pathway
          positive regulation of extrinsic apoptotic signaling pathway
          DNA binding
          transcription coactivator activity
          protein binding
          zinc ion binding
          ubiquitin protein ligase binding
          SUMO binding
          protein homodimerization activity
          SMAD binding
          metal ion binding
          protein heterodimerization activity
          cobalt ion binding

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