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          System Message

          OKCancel
          LOADING ...
          See other IL1B SIRNA Assays ›
          Gene Symbol:
          IL1B
          Gene Name:
          interleukin 1 beta
          Gene Aliases:
          IL-1, IL1-BETA, IL1F2
          Chromosome Location:
          Chr.2: 112829758 - 112836842 on Build GRCh38
          UniGene ID:
          Hs.126256
          Species:
          Human
          Species Specific ID (Flybase ID):
          -
          siRNA ID HSS105299
          Size 20 nmol
          Availability Made To Order
          Catalog # 1299001
          Price
          Your Price
          Online offer:
          Check your price ›
          • Genomic Map
          • siRNA Details
          • More Information

          Genomic Map

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          siRNA Details

          Gene Symbol: IL1B
          Interrogated Sequence Translated Protein Targeted Exon(s) siRNA Location IMAGE Clone ID
          RefSeq NM_000576.2 NP_000567.1 3 154
          XM_017003988.1 XP_016859477.1 2 155
          GenBank mRNA AK313983.1 - 2 617
          BC008678.1 - 3 154 3875593
          BT007213.1 - 2 67
          CR407679.1 - 2 67
          K02770.1 - 3 153
          M15330.1 - 3 153
          X02532.1 - 3 144
          X56087.1 - 3 124

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          More Information


          Panther Classification:

          Molecular Function -

          interleukin superfamily

          Gene Ontology Categories:

          Function(s) Process(es)

          negative regulation of transcription from RNA polymerase II promoter
          MAPK cascade
          activation of MAPK activity
          fever generation
          response to hypoxia
          positive regulation of protein phosphorylation
          chronic inflammatory response to antigenic stimulus
          positive regulation of T cell mediated immunity
          purine nucleobase metabolic process
          apoptotic process
          inflammatory response
          signal transduction
          positive regulation of cytosolic calcium ion concentration
          cell-cell signaling
          embryo implantation
          aging
          memory
          estrogen metabolic process
          negative regulation of cell proliferation
          glycoprotein metabolic process
          response to heat
          response to ozone
          response to gamma radiation
          positive regulation of vascular endothelial growth factor production
          positive regulation of gene expression
          negative regulation of glucose transport
          negative regulation of glutamate secretion
          smooth muscle adaptation
          cytokine-mediated signaling pathway
          pentacyclic triterpenoid metabolic process
          hyaluronan biosynthetic process
          neutrophil chemotaxis
          polyketide metabolic process
          ovulation
          sequestering of triglyceride
          positive regulation of vascular endothelial growth factor receptor signaling pathway
          positive regulation of fever generation
          lipopolysaccharide-mediated signaling pathway
          positive regulation of prostaglandin secretion
          response to estradiol
          interleukin-1 beta production
          positive regulation of granulocyte macrophage colony-stimulating factor production
          positive regulation of interferon-gamma production
          positive regulation of interleukin-6 production
          positive regulation of interleukin-8 production
          positive regulation of immature T cell proliferation in thymus
          positive regulation of histone phosphorylation
          response to ATP
          response to vitamin D
          response to L-ascorbic acid
          positive regulation of heterotypic cell-cell adhesion
          positive regulation of histone acetylation
          social behavior
          ectopic germ cell programmed cell death
          positive regulation of myosin light chain kinase activity
          response to stilbenoid
          cellular response to drug
          response to diuretic
          response to statin
          wound healing
          positive regulation of T cell proliferation
          positive regulation of NF-kappaB import into nucleus
          positive regulation of apoptotic process
          regulation of I-kappaB kinase/NF-kappaB signaling
          response to morphine
          negative regulation of MAP kinase activity
          response to peptide hormone
          protein kinase B signaling
          positive regulation of JUN kinase activity
          positive regulation of chemokine biosynthetic process
          positive regulation of interleukin-2 biosynthetic process
          positive regulation of interleukin-6 biosynthetic process
          positive regulation of nitric oxide biosynthetic process
          response to ethanol
          negative regulation of neuron differentiation
          positive regulation of angiogenesis
          negative regulation of lipid metabolic process
          positive regulation of mitotic nuclear division
          positive regulation of transcription, DNA-templated
          positive regulation of transcription from RNA polymerase II promoter
          positive regulation of JNK cascade
          negative regulation of insulin receptor signaling pathway
          positive regulation of protein export from nucleus
          positive regulation of astrocyte differentiation
          positive regulation of phagocytosis
          regulation of insulin secretion
          negative regulation of lipid catabolic process
          positive regulation of lipid catabolic process
          regulation of nitric-oxide synthase activity
          positive regulation of membrane protein ectodomain proteolysis
          positive regulation of sequence-specific DNA binding transcription factor activity
          positive regulation of NF-kappaB transcription factor activity
          positive regulation of cell division
          positive regulation of cell adhesion molecule production
          positive regulation of calcidiol 1-monooxygenase activity
          negative regulation of adiponectin secretion
          positive regulation of ERK1 and ERK2 cascade
          monocyte aggregation
          cellular response to antibiotic
          cellular response to mechanical stimulus
          cellular response to organic substance
          cellular response to glucose stimulus
          cellular response to fatty acid
          cellular response to organic cyclic compound
          cellular response to methotrexate
          response to dexamethasone
          positive regulation of monocyte chemotactic protein-1 production
          positive regulation of neutrophil chemotaxis
          extrinsic apoptotic signaling pathway in absence of ligand
          regulation of establishment of endothelial barrier
          negative regulation of branching morphogenesis of a nerve
          negative regulation of neural precursor cell proliferation
          positive regulation of interleukin-6 secretion
          negative regulation of extrinsic apoptotic signaling pathway in absence of ligand
          cytokine activity
          interleukin-1 receptor binding
          protein domain specific binding

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