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          System Message

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          LOADING ...
          See other TRP53 SIRNA Assays ›
          Gene Symbol:
          Trp53
          Gene Name:
          transformation related protein 53
          Gene Aliases:
          Tp53, bbl, bfy, bhy, p44, p53
          Chromosome Location:
          Chr.11: 69580359 - 69591873 on Build GRCm38
          UniGene ID:
          Mm.222
          Species:
          Mouse
          Species Specific ID (Flybase ID):
          -
          siRNA ID MSS212110
          Size 20 nmol
          Availability Made To Order
          Catalog # 1320001
          Price Contact Us
          Your Price
          Online offer:
          Check your price ›
          • Genomic Map
          • siRNA Details
          • More Information

          Genomic Map

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          siRNA Details

          Gene Symbol: Trp53
          Interrogated Sequence Translated Protein Targeted Exon(s) siRNA Location IMAGE Clone ID
          RefSeq NM_001127233.1 NP_001120705.1 2 175
          NM_011640.3 NP_035770.2 2 175
          GenBank mRNA AB017815.1 - 2 119
          AB017816.1 - 2 119
          AB020317.1 - 2 119
          AB021961.1 - 2 118
          AB221571.1 - 1 18
          AF051368.1 - 2 43
          AF151353.1 - 2 140
          AF161020.1 - 1 28
          AJ297973.1 - 1 18
          AK079711.1 - 2 132
          AK083750.1 - 2 133
          AK086845.1 - 2 154
          AK087834.1 - 2 132
          AK138777.1 - 3 544
          AK147815.1 - 2 132
          AY044188.1 - 1 18
          AY212017.1 - 2 129
          BC005448.1 - 2 146 3599812
          EU031806.1 - 2 80
          KF766124.1 - 1 18
          M13872.1 - 2 130
          M13873.1 - 2 86
          M13874.1 - 2 71
          X00741.1 - 2 140
          X01237.1 - 2 175

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          More Information


          Panther Classification:

          Molecular Function -

          P53-like transcription factor

          Gene Ontology Categories:

          Function(s) Process(es)

          protein import into nucleus, translocation
          negative regulation of transcription from RNA polymerase II promoter
          DNA strand renaturation
          in utero embryonic development
          somitogenesis
          release of cytochrome c from mitochondria
          T cell proliferation involved in immune response
          B cell lineage commitment
          T cell lineage commitment
          positive regulation of leukocyte migration
          response to ischemia
          nucleotide-excision repair
          double-strand break repair
          transcription, DNA-templated
          regulation of transcription, DNA-templated
          regulation of transcription from RNA polymerase II promoter
          transcription from RNA polymerase II promoter
          protein complex assembly
          apoptotic process
          cellular response to DNA damage stimulus
          DNA damage response, signal transduction by p53 class mediator resulting in cell cycle arrest
          DNA damage response, signal transduction by p53 class mediator resulting in transcription of p21 class mediator
          response to oxidative stress
          ER overload response
          cell cycle
          cell cycle arrest
          transforming growth factor beta receptor signaling pathway
          multicellular organism development
          gastrulation
          negative regulation of neuroblast proliferation
          central nervous system development
          cell aging
          protein localization
          negative regulation of DNA replication
          negative regulation of cell proliferation
          determination of adult lifespan
          rRNA transcription
          response to UV
          response to salt stress
          embryo development ending in birth or egg hatching
          response to X-ray
          response to gamma radiation
          positive regulation of cardiac muscle cell apoptotic process
          programmed cell death
          viral process
          cerebellum development
          negative regulation of cell growth
          DNA damage response, signal transduction by p53 class mediator
          negative regulation of transforming growth factor beta receptor signaling pathway
          chromosome breakage
          positive regulation of histone deacetylation
          chromatin assembly
          mitotic G1 DNA damage checkpoint
          positive regulation of protein oligomerization
          T cell differentiation in thymus
          regulation of tissue remodeling
          cellular protein localization
          cellular response to UV
          multicellular organism growth
          positive regulation of mitochondrial membrane permeability
          regulation of cell proliferation
          cellular response to glucose starvation
          response to drug
          intrinsic apoptotic signaling pathway in response to DNA damage by p53 class mediator
          regulation of apoptotic process
          positive regulation of apoptotic process
          negative regulation of apoptotic process
          entrainment of circadian clock by photoperiod
          mitochondrial DNA repair
          regulation of neuron apoptotic process
          positive regulation of neuron apoptotic process
          positive regulation of cell cycle
          negative regulation of proteolysis
          negative regulation of transcription, DNA-templated
          positive regulation of transcription, DNA-templated
          negative regulation of mitotic cell cycle
          positive regulation of transcription from RNA polymerase II promoter
          negative regulation of fibroblast proliferation
          rhythmic process
          circadian behavior
          embryonic organ development
          negative regulation of smooth muscle cell proliferation
          positive regulation of peptidyl-tyrosine phosphorylation
          regulation of catalytic activity
          protein tetramerization
          chromosome organization
          neuron apoptotic process
          regulation of intracellular pH
          regulation of cell cycle
          positive regulation of transcription from RNA polymerase II promoter in response to hypoxia
          intrinsic apoptotic signaling pathway in response to endoplasmic reticulum stress
          regulation of thymocyte apoptotic process
          positive regulation of thymocyte apoptotic process
          necroptotic process
          positive regulation of cell cycle arrest
          cellular response to ionizing radiation
          cellular response to UV-C
          mitotic cell cycle arrest
          intrinsic apoptotic signaling pathway by p53 class mediator
          regulation of glycolytic process by positive regulation of transcription from RNA polymerase II promoter
          positive regulation of release of cytochrome c from mitochondria
          positive regulation of cell aging
          replicative senescence
          oxidative stress-induced premature senescence
          oligodendrocyte apoptotic process
          positive regulation of execution phase of apoptosis
          negative regulation of macromitophagy
          regulation of mitochondrial membrane permeability involved in apoptotic process
          regulation of intrinsic apoptotic signaling pathway by p53 class mediator
          regulation of hydrogen peroxide-induced cell death
          negative regulation of glucose catabolic process to lactate via pyruvate
          intrinsic apoptotic signaling pathway in response to hypoxia
          positive regulation of transcription from RNA polymerase II promoter in response to endoplasmic reticulum stress
          regulation of fibroblast apoptotic process
          negative regulation of DNA biosynthetic process
          negative regulation of reactive oxygen species metabolic process
          positive regulation of reactive oxygen species metabolic process
          regulation of cellular senescence
          positive regulation of intrinsic apoptotic signaling pathway
          RNA polymerase II regulatory region sequence-specific DNA binding
          RNA polymerase II core promoter sequence-specific DNA binding
          RNA polymerase II transcription factor activity, sequence-specific DNA binding
          core promoter sequence-specific DNA binding
          transcriptional activator activity, RNA polymerase II core promoter proximal region sequence-specific binding
          RNA polymerase II transcription factor binding
          transcription cofactor binding
          transcriptional activator activity, RNA polymerase II transcription regulatory region sequence-specific binding
          protease binding
          p53 binding
          DNA binding
          chromatin binding
          damaged DNA binding
          double-stranded DNA binding
          transcription factor activity, sequence-specific DNA binding
          copper ion binding
          protein binding
          ATP binding
          protein C-terminus binding
          transcription factor binding
          enzyme binding
          protein kinase binding
          protein phosphatase binding
          receptor tyrosine kinase binding
          ubiquitin protein ligase binding
          histone deacetylase regulator activity
          histone acetyltransferase binding
          identical protein binding
          sequence-specific DNA binding
          protein self-association
          transcription regulatory region DNA binding
          metal ion binding
          protein heterodimerization activity
          protein N-terminus binding
          chaperone binding
          protein phosphatase 2A binding
          MDM2/MDM4 family protein binding

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