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          System Message

          OKCancel
          LOADING ...
          See other CASP8 SIRNA Assays ›
          Gene Symbol:
          CASP8
          Gene Name:
          caspase 8
          Gene Aliases:
          ALPS2B, CAP4, Casp-8, FLICE, MACH, MCH5
          Chromosome Location:
          Chr.2: 201233443 - 201287711 on Build GRCh38
          UniGene ID:
          Hs.599762
          Species:
          Human
          Species Specific ID (Flybase ID):
          -
          siRNA ID s2425

          Purification
          Size
          Availability Inventoried
          Catalog # 4392420
          Price 388.00
          Your Price
          Online offer: 374.65
          374.65
          Check your price ›
          • Genomic Map
          • siRNA Details
          • More Information

          Genomic Map

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          siRNA Details

          Gene Symbol: CASP8
          Interrogated Sequence Translated Protein Targeted Exon(s) siRNA Location IMAGE Clone ID
          RefSeq NM_001080124.1 NP_001073593.1 5 762
          NM_001080125.1 NP_001073594.1 4 905
          NM_001228.4 NP_001219.2 6 926
          NM_033355.3 NP_203519.1 5 736
          NM_033356.3 NP_203520.1 4 667
          NM_033358.3 NP_203522.1 5 830
          NR_111983.1 4 905
          XM_005246885.1 XP_005246942.1 4 725
          XM_005246886.1 XP_005246943.1 4 651
          XM_005246887.1 XP_005246944.1 5 803
          XM_005246888.1 XP_005246945.1 5 745
          XM_005246889.1 XP_005246946.1 4 622
          XM_005246890.3 XP_005246947.1 4 629
          XM_005246891.4 XP_005246948.1 4 869
          XM_005246892.1 XP_005246949.1 4 622
          XM_005246893.2 XP_005246950.1 4 725
          XM_005246894.3 XP_005246951.1 5 800
          XM_005246895.2 XP_005246952.1 4 725
          XM_006712789.1 XP_006712852.1 5 762
          XM_006712790.3 XP_006712853.1 4 641
          XM_006712793.2 XP_006712856.1 5 803
          XM_011511969.1 XP_011510271.1 2 206
          GenBank mRNA AB451282.1 - 3 527
          AB451414.1 - 3 527
          AF009620.1 - 3 527
          AF380342.1 - 4 612
          AF422927.1 - 5 750
          AF422928.1 - 5 724
          AK310630.1 - 5 803
          BC028223.2 - 3 554
          BC068050.1 - 4 617 6421760
          BX395849.2 - 4 616
          EU168332.1 - 3 527
          JN657192.1 - 3 489
          U58143.1 - 3 527
          U60520.1 - 6 879
          X98172.1 - 4 818
          X98173.1 - 4 599
          X98174.1 - 2 142
          X98175.1 - 2 142
          X98176.1 - 5 716
          X98177.1 - 3 527
          X98178.1 - 3 527

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          More Information


          Panther Classification:

          Molecular Function -

          protease

          Gene Ontology Categories:

          Function(s) Process(es)

          proteolysis
          apoptotic process
          activation of cysteine-type endopeptidase activity involved in apoptotic process
          cellular component disassembly involved in execution phase of apoptosis
          cell surface receptor signaling pathway
          response to cold
          regulation of tumor necrosis factor-mediated signaling pathway
          regulation of necrotic cell death
          natural killer cell activation
          macrophage differentiation
          response to cobalt ion
          response to estradiol
          response to lipopolysaccharide
          response to tumor necrosis factor
          TRIF-dependent toll-like receptor signaling pathway
          TRAIL-activated apoptotic signaling pathway
          suppression by virus of host cysteine-type endopeptidase activity involved in apoptotic process
          T cell activation
          B cell activation
          positive regulation of I-kappaB kinase/NF-kappaB signaling
          negative regulation of I-kappaB kinase/NF-kappaB signaling
          response to ethanol
          positive regulation of macrophage differentiation
          positive regulation of proteolysis
          response to antibiotic
          protein heterooligomerization
          proteolysis involved in cellular protein catabolic process
          syncytiotrophoblast cell differentiation involved in labyrinthine layer development
          nucleotide-binding oligomerization domain containing signaling pathway
          cellular response to mechanical stimulus
          cellular response to organic cyclic compound
          death-inducing signaling complex assembly
          apoptotic signaling pathway
          extrinsic apoptotic signaling pathway
          execution phase of apoptosis
          activation of cysteine-type endopeptidase activity
          activation of cysteine-type endopeptidase activity involved in apoptotic signaling pathway
          positive regulation of protein insertion into mitochondrial membrane involved in apoptotic signaling pathway
          regulation of extrinsic apoptotic signaling pathway via death domain receptors
          negative regulation of extrinsic apoptotic signaling pathway via death domain receptors
          cysteine-type endopeptidase activity
          death receptor binding
          tumor necrosis factor receptor binding
          protein binding
          peptidase activity
          cysteine-type peptidase activity
          ubiquitin protein ligase binding
          protein complex binding
          death effector domain binding
          identical protein binding
          scaffold protein binding
          cysteine-type endopeptidase activity involved in apoptotic process
          cysteine-type endopeptidase activity involved in apoptotic signaling pathway

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