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          System Message

          OKCancel
          LOADING ...
          See other EDN1 SIRNA Assays ›
          Gene Symbol:
          EDN1
          Gene Name:
          endothelin 1
          Gene Aliases:
          ARCND3, ET1, HDLCQ7, PPET1, QME
          Chromosome Location:
          Chr.6: 12256464 - 12297194 on Build GRCh38
          UniGene ID:
          Hs.511899
          Species:
          Human
          Species Specific ID (Flybase ID):
          -
          siRNA ID s4457

          Purification
          Size
          Availability Inventoried
          Catalog # 4392420
          Price 388.00
          Your Price
          Online offer: 374.65
          374.65
          Check your price ›
          • Genomic Map
          • siRNA Details
          • More Information

          Genomic Map

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          siRNA Details

          Gene Symbol: EDN1
          Interrogated Sequence Translated Protein Targeted Exon(s) siRNA Location IMAGE Clone ID
          RefSeq NM_001168319.1 NP_001161791.1 4 844
          NM_001955.4 NP_001946.3 4 847
          XM_011514330.2 XP_011512632.1 5 603
          XM_011514331.2 XP_011512633.1 6 764
          XM_011514332.2 XP_011512634.1 5 601
          XM_017010331.1 XP_016865820.1 5 787
          GenBank mRNA AK226096.1 - 4 762
          AK291838.1 - 4 784
          AK313914.1 - 4 779
          BC009720.1 - 4 716 3900704
          BX439515.2 - 4 807
          CR541903.1 - 4 513
          S56805.1 - 4 849
          Y00749.1 - 4 765

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          More Information


          Panther Classification:

          Molecular Function -

          peptide hormone

          Gene Ontology Categories:

          Function(s) Process(es)

          negative regulation of transcription from RNA polymerase II promoter
          prostaglandin biosynthetic process
          patterning of blood vessels
          in utero embryonic development
          histamine secretion
          regulation of systemic arterial blood pressure by endothelin
          regulation of pH
          cell surface receptor signaling pathway
          G-protein coupled receptor signaling pathway
          positive regulation of cytosolic calcium ion concentration
          protein kinase C-activating G-protein coupled receptor signaling pathway
          cell-cell signaling
          heart development
          respiratory gaseous exchange
          body fluid secretion
          positive regulation of cell proliferation
          dorsal/ventral pattern formation
          response to ozone
          multicellular organism aging
          positive regulation of heart rate
          positive regulation of endothelial cell migration
          positive regulation of cardiac muscle hypertrophy
          positive regulation of receptor biosynthetic process
          neural crest cell development
          phosphatidylinositol 3-kinase signaling
          response to activity
          artery smooth muscle contraction
          vein smooth muscle contraction
          glucose transport
          cell growth
          regulation of vasoconstriction
          sensory perception of pain
          calcium-mediated signaling
          peptide hormone secretion
          nitric oxide transport
          negative regulation of blood coagulation
          positive regulation of cell migration
          neutrophil chemotaxis
          negative regulation of cAMP biosynthetic process
          phospholipase D-activating G-protein coupled receptor signaling pathway
          negative regulation of cellular protein metabolic process
          positive regulation of prostaglandin secretion
          response to lipopolysaccharide
          response to testosterone
          negative regulation of smooth muscle cell apoptotic process
          response to prostaglandin F
          response to nicotine
          cellular response to drug
          positive regulation of urine volume
          positive regulation of renal sodium excretion
          response to muscle stretch
          epithelial fluid transport
          vasoconstriction
          protein kinase C deactivation
          middle ear morphogenesis
          positive regulation of odontogenesis
          superoxide anion generation
          rhythmic excitation
          response to amino acid
          positive regulation of MAP kinase activity
          positive regulation of JUN kinase activity
          response to leptin
          leukocyte activation
          positive regulation of nitric oxide biosynthetic process
          positive regulation of cell size
          positive regulation of mitotic nuclear division
          positive regulation of transcription from RNA polymerase II promoter
          positive regulation of smooth muscle contraction
          positive regulation of hormone secretion
          negative regulation of hormone secretion
          inositol phosphate-mediated signaling
          positive regulation of smooth muscle cell proliferation
          positive regulation of sequence-specific DNA binding transcription factor activity
          cartilage development
          positive regulation of cytosolic calcium ion concentration involved in phospholipase C-activating G-protein coupled signaling pathway
          negative regulation of nitric-oxide synthase biosynthetic process
          membrane depolarization
          regulation of sensory perception of pain
          maternal process involved in parturition
          positive regulation of sarcomere organization
          positive regulation of prostaglandin-endoperoxide synthase activity
          positive regulation of cell growth involved in cardiac muscle cell development
          positive regulation of chemokine-mediated signaling pathway
          cellular response to calcium ion
          cellular response to interferon-gamma
          cellular response to interleukin-1
          cellular response to tumor necrosis factor
          cellular response to peptide hormone stimulus
          cellular response to glucocorticoid stimulus
          cellular response to mineralocorticoid stimulus
          cellular response to fatty acid
          cellular response to hypoxia
          response to dexamethasone
          cellular response to transforming growth factor beta stimulus
          response to salt
          cytokine activity
          hormone activity
          protein binding
          endothelin A receptor binding
          endothelin B receptor binding

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